C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: renin 1 structural
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000070645 Ren1 10090 + 1:133350510-133360325 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000094556 Ren1-001 133350510-133360325 protein_coding
  ENSMUST00000112287 Ren1-002 133351909-133354276 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000094556
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000094556 0.448±0.21 2.949±1.23 0.086±0.03 1.081±0.40 0.136±0.07 0.135±0.07 0.108±0.05 92.255±19.27 1.228±1.71 0.070±0.00 0.036±0.00 3.758±1.12 0.281±0.30 0.674±0.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00084Z CIL_00084Z_0002 VISTA 1:132779893-133380922
CIL_0008W2 CIL_0008W2_0002 VISTA 1:133249313-133850886

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001822 IEA kidney development
GO:0001823 IEP mesonephros development
GO:0002003 IMP angiotensin maturation
GO:0002016 IMP regulation of blood volume by renin-angiotensin
GO:0002018 IDA renin-angiotensin regulation of aldosterone production
GO:0004175 IDA endopeptidase activity
GO:0005102 IEA receptor binding
GO:0005159 IEA insulin-like growth factor receptor binding
GO:0005615 IDA extracellular space
GO:0005622 IDA intracellular
GO:0005737 IEA cytoplasm
GO:0008233 IEA peptidase activity
GO:0008584 IEP male gonad development
GO:0009755 IDA hormone-mediated signaling pathway
GO:0010033 IDA response to organic substance
GO:0016020 IEA membrane
GO:0032496 IEA response to lipopolysaccharide
GO:0035690 IEA cellular response to drug
GO:0035902 IEA response to immobilization stress
GO:0042493 IEA response to drug
GO:0042756 IMP drinking behavior
GO:0043408 IEA regulation of MAPK cascade
GO:0048469 IMP cell maturation
GO:0050435 IEA beta-amyloid metabolic process
GO:0051591 IEA response to cAMP
GO:0070305 IEA response to cGMP

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041858 ren renin protein_coding Danio_rerio
ENSG00000143839 REN renin protein_coding Homo_sapiens

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