C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth differentiation factor 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143869 GDF7 9606 + 2:20666664-20673658 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000272224 GDF7-001 20666664-20673658 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000272224
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000272224 0.078±0.00 1.315±0.00 0.173±0.03 0.273±0.25 0.269±0.02 0.129±0.08 1.005±0.31 0.925±0.56 0.166±0.03 0.048±0.00 0.074±0.05 0.412±0.25 0.328±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PO CIL_0008PO_0001 VISTA 2:20278534-20880046

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005615 IEA extracellular space
GO:0007411 IEA axon guidance
GO:0008083 IEA growth factor activity
GO:0010628 IEA positive regulation of gene expression
GO:0010862 IDA positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0021509 IEA roof plate formation
GO:0021527 IEA spinal cord association neuron differentiation
GO:0021915 IEA neural tube development
GO:0022612 IEA gland morphogenesis
GO:0030509 IDA BMP signaling pathway
GO:0030855 IEA epithelial cell differentiation
GO:0030901 IEA midbrain development
GO:0032924 IDA activin receptor signaling pathway
GO:0040007 IEA growth
GO:0042803 IEA protein homodimerization activity
GO:0045165 IEA cell fate commitment
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048608 IEA reproductive structure development
GO:0048754 IEA branching morphogenesis of an epithelial tube
GO:0048853 IEA forebrain morphogenesis
GO:0060389 IDA pathway-restricted SMAD protein phosphorylation
GO:0060571 IEA morphogenesis of an epithelial fold
GO:2001051 IEA positive regulation of tendon cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000037660 Gdf7 growth differentiation factor 7 protein_coding Mus_musculus

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