C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: speckle-type POZ protein-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000144228 SPOPL 9606 + 2:138501801-138573547 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000280098 SPOPL-001 138501801-138573547 protein_coding
  ENST00000420679 SPOPL-002 138550157-138569130 nonsense_mediated_decay
  ENST00000430968 SPOPL-003 138501932-138552582 nonsense_mediated_decay
  ENST00000467775 SPOPL-004 138564388-138565019 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000280098ENST00000420679
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000280098 0.648±0.00 2.023±0.00 0.856±0.11 2.168±0.64 2.349±0.09 1.381±0.54 1.035±0.00 2.671±1.48 3.705±0.00 0.734±0.47 1.482±0.50 1.154±0.00 2.568±0.00
ENST00000420679 N/A N/A 1.049±0.00 3.173±0.00 1.888±0.00 N/A 2.716±0.00 3.240±0.00 3.942±0.00 0.738±0.00 3.185±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0016567 IEA protein ubiquitination
GO:0031397 IMP negative regulation of protein ubiquitination
GO:0031463 IDA Cul3-RING ubiquitin ligase complex
GO:0043161 IMP proteasome-mediated ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003974 spoplb speckle-type POZ protein-like b protein_coding Danio_rerio
ENSDARG00000010563 spopla speckle-type POZ protein-like a protein_coding Danio_rerio
ENSMUSG00000026771 Spopl speckle-type POZ protein-like protein_coding Mus_musculus

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