C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal recognition particle receptor, B subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000144867 SRPRB 9606 + 3:133784033-133825772 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000466490 SRPRB-001 133784033-133821492 protein_coding
  ENST00000466636 SRPRB-005 133811124-133825772 nonsense_mediated_decay
  ENST00000481356 SRPRB-002 133810262-133819909 retained_intron
  ENST00000484684 SRPRB-003 133805615-133807774 protein_coding
  ENST00000494297 SRPRB-004 133806553-133819603 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastHeartLungMuscleOvaryPlacentaTestisENST00000466490ENST00000481356ENST00000484684ENST00000494297
Transcript ID Adipose Adrenal Bladder Breast Heart Lung Muscle Ovary Placenta Testis
ENST00000466490 6.183±0.00 10.538±0.00 N/A N/A 3.839±0.00 3.552±0.00 2.323±0.00 6.153±0.14 9.263±0.00 14.613±0.00
ENST00000481356 N/A N/A 1.641±0.00 2.015±0.00 N/A N/A 0.760±0.00 1.691±0.00 N/A N/A
ENST00000484684 N/A N/A N/A N/A N/A 6.684±0.00 N/A N/A N/A N/A
ENST00000494297 11.201±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 15.104±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005525 IEA GTP binding
GO:0005634 IEA nucleus
GO:0005737 IDA:IEA cytoplasm
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005881 IDA cytoplasmic microtubule
GO:0006412 TAS translation
GO:0006614 TAS SRP-dependent cotranslational protein targeting to membrane
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0007264 IEA small GTPase mediated signal transduction
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0044267 TAS cellular protein metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030949 srprb signal recognition particle receptor, B subunit protein_coding Danio_rerio
ENSMUSG00000032553 Srprb signal recognition particle receptor, B subunit protein_coding Mus_musculus

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