C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: EPH receptor A5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145242 EPHA5 9606 - 4:65319563-65670495 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000273854 EPHA5-001 65319563-65670343 protein_coding
  ENST00000354839 EPHA5-002 65323928-65669935 protein_coding
  ENST00000432638 EPHA5-003 65323395-65670060 protein_coding
  ENST00000511294 EPHA5-004 65330561-65670495 protein_coding
  ENST00000613740 EPHA5-201 65319563-65670495 protein_coding
  ENST00000622150 EPHA5-202 65319563-65670495 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000273854ENST00000354839ENST00000432638ENST00000511294ENST00000613740ENST00000622150
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000273854 N/A 0.007±0.00 1.379±0.19 0.009±0.00 N/A 0.033±0.00 N/A N/A 0.029±0.00 0.063±0.00 0.014±0.01 0.050±0.00
ENST00000354839 0.025±0.00 0.009±0.00 1.337±0.00 N/A N/A N/A 0.239±0.00 0.032±0.00 N/A N/A 0.033±0.00 0.507±0.00
ENST00000432638 N/A N/A N/A 0.046±0.03 0.057±0.00 0.011±0.00 0.110±0.00 0.037±0.00 N/A 0.112±0.00 N/A 0.122±0.00
ENST00000511294 0.006±0.00 N/A 4.339±0.00 0.021±0.00 N/A N/A N/A N/A N/A N/A 0.021±0.00 N/A
ENST00000613740 N/A 0.010±0.00 0.832±0.00 0.010±0.00 N/A 0.009±0.00 0.098±0.00 N/A N/A 0.071±0.05 0.009±0.01 0.087±0.04
ENST00000622150 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.193±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001WK CIL_0001WK_0001 CGP 4:64275257-65670495
CIL_0000M8 CIL_0000M8_0001 CGP 4:65319563-67545606

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005003 ISS:IEA ephrin receptor activity
GO:0005004 ISS GPI-linked ephrin receptor activity
GO:0005005 NAS transmembrane-ephrin receptor activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005791 IDA rough endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007411 ISS axon guidance
GO:0009897 IDA external side of plasma membrane
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019933 ISS cAMP-mediated signaling
GO:0021766 ISS hippocampus development
GO:0030425 IDA dendrite
GO:0032314 ISS regulation of Rac GTPase activity
GO:0032793 ISS positive regulation of CREB transcription factor activity
GO:0032956 ISS regulation of actin cytoskeleton organization
GO:0043025 IDA neuronal cell body
GO:0048013 ISS:IEA ephrin receptor signaling pathway
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048666 IEP neuron development
GO:0051964 IEA negative regulation of synapse assembly
GO:0061178 ISS regulation of insulin secretion involved in cellular response to glucose stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058284 CT990561.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000029245 Epha5 Eph receptor A5 protein_coding Mus_musculus

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