C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dedicator of cytokinesis 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147251 DOCK11 9606 + X:118495898-118686163 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000276202 DOCK11-003 118495909-118686147 protein_coding
  ENST00000276204 DOCK11-001 118495898-118686163 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000276202ENST00000276204
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000276202 11.687±0.00 4.631±0.00 N/A 0.392±0.00 12.464±3.62 2.947±0.67 0.931±0.37 2.080±1.55 2.212±1.88 3.770±1.39 0.473±0.07 1.360±0.25 1.731±0.38 1.536±0.29
ENST00000276204 N/A N/A 0.672±0.00 0.387±0.00 N/A 0.850±0.00 N/A N/A N/A N/A N/A 0.491±0.00 N/A 0.917±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000714 CIL_000714_0001 CGP X:118495898-118794539

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005829 TAS cytosol
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007596 TAS blood coagulation
GO:0017048 IEA Rho GTPase binding
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062485 dock11 dedicator of cytokinesis 11 protein_coding Danio_rerio
ENSMUSG00000031093 Dock11 dedicator of cytokinesis 11 protein_coding Mus_musculus

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