C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dedicator of cytokinesis 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031093 Dock11 10090 + X:35888832-36076562 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033419 Dock11-001 35888832-36076562 protein_coding
  ENSMUST00000115264 Dock11-004 36041238-36076227 protein_coding
  ENSMUST00000115266 Dock11-003 35947397-36076556 protein_coding
  ENSMUST00000140175 Dock11-005 36011427-36016839 retained_intron
  ENSMUST00000145757 Dock11-002 35974888-35983839 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033419ENSMUST00000115264ENSMUST00000115266ENSMUST00000140175
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033419 0.999±0.20 0.290±0.13 0.287±0.03 1.903±0.97 1.008±0.48 0.176±0.00 0.223±0.17 0.250±0.17 0.290±0.20 0.466±0.12 0.150±0.08 0.770±0.26 0.948±0.44 0.241±0.01
ENSMUST00000115264 N/A N/A 0.774±0.10 3.420±1.00 N/A N/A N/A 0.089±0.00 0.523±0.30 N/A 0.305±0.11 2.951±0.00 4.094±3.07 0.491±0.00
ENSMUST00000115266 N/A N/A 0.685±0.01 0.746±0.38 1.569±0.00 N/A N/A 0.163±0.00 0.312±0.19 N/A 0.103±0.05 1.177±0.28 1.098±0.55 0.128±0.05
ENSMUST00000140175 N/A 0.924±0.00 N/A N/A N/A N/A N/A N/A 0.253±0.02 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000714 CIL_000714_0002 CGP X:35888832-36171259

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IDA Rho guanyl-nucleotide exchange factor activity
GO:0005575 ND cellular_component
GO:0007264 IEA small GTPase mediated signal transduction
GO:0017048 IPI Rho GTPase binding
GO:0032321 IDA positive regulation of Rho GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062485 dock11 dedicator of cytokinesis 11 protein_coding Danio_rerio
ENSG00000147251 DOCK11 dedicator of cytokinesis 11 protein_coding Homo_sapiens

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