C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HECT and RLD domain containing E3 ubiquitin protein ligase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148634 HERC4 9606 - 10:67921899-68075348 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000277817 HERC4-002 67921899-68039967 protein_coding
  ENST00000373700 HERC4-001 67922489-68075348 protein_coding
  ENST00000395185 HERC4-011 68067085-68075301 processed_transcript
  ENST00000395198 HERC4-009 67921908-68075283 protein_coding
  ENST00000412272 HERC4-008 67921908-68075283 protein_coding
  ENST00000427635 HERC4-010 67922484-68073097 nonsense_mediated_decay
  ENST00000460168 HERC4-004 67964792-67990241 retained_intron
  ENST00000463478 HERC4-007 68032819-68038365 retained_intron
  ENST00000473533 HERC4-016 67922484-68075283 nonsense_mediated_decay
  ENST00000480158 HERC4-003 67954200-67956861 processed_transcript
  ENST00000492996 HERC4-006 68067689-68075283 protein_coding
  ENST00000505760 HERC4-012 68067182-68074857 processed_transcript
  ENST00000506515 HERC4-013 68073021-68074137 protein_coding
  ENST00000513996 HERC4-015 68034000-68075257 protein_coding
  ENST00000515753 HERC4-014 68073135-68074193 processed_transcript

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000277817ENST00000373700ENST00000395198ENST00000460168ENST00000473533ENST00000492996
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000277817 N/A N/A N/A 1.747±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000373700 2.876±0.00 3.791±0.00 2.783±0.00 2.139±0.32 4.538±0.67 5.540±0.91 2.739±0.60 5.046±0.71 3.759±3.05 4.571±2.68 2.423±0.00 5.982±3.09 3.474±2.23 6.886±1.21
ENST00000395198 1.423±0.00 N/A N/A 2.670±0.92 1.698±0.00 N/A 1.423±0.00 3.075±0.00 1.423±0.00 0.921±0.00 0.919±0.13 1.854±0.00 1.617±0.28 N/A
ENST00000460168 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.491±0.00 N/A N/A N/A
ENST00000473533 N/A N/A N/A N/A N/A N/A N/A N/A 0.782±0.00 1.195±0.00 N/A 2.337±0.00 N/A N/A
ENST00000492996 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.724±0.00 0.828±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IBA:IEA ubiquitin-protein transferase activity
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0007283 ISS spermatogenesis
GO:0016874 IEA ligase activity
GO:0030154 IEA cell differentiation
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059936 HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 protein_coding Danio_rerio
ENSMUSG00000020064 Herc4 hect domain and RLD 4 protein_coding Mus_musculus

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