C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NK6 homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148826 NKX6-2 9606 - 10:132783179-132786052 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368592 NKX6-2-001 132783181-132786052 protein_coding
  ENST00000441365 NKX6-2-002 132783179-132784765 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000368592ENST00000441365
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000368592 N/A N/A 3.088±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000441365 24.704±0.00 42.493±0.00 N/A 52.216±0.00 114.569±0.00 32.971±0.00 22.106±0.00 39.136±0.00 45.694±11.88 29.022±0.00 52.512±15.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W3 CIL_0008W3_0001 VISTA 10:132328525-132933308
CIL_0000BD CIL_0000BD_0001 CGP 10:132537820-132786052

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IEA DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0005634 NAS nucleus
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0010454 IEA negative regulation of cell fate commitment
GO:0010455 IEA positive regulation of cell fate commitment
GO:0021912 IEA regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
GO:0021913 IEA regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
GO:0022010 IEA central nervous system myelination
GO:0030154 IEA cell differentiation
GO:0031018 IEA endocrine pancreas development
GO:0043565 IEA sequence-specific DNA binding
GO:0045686 IEA negative regulation of glial cell differentiation
GO:0045687 IEA positive regulation of glial cell differentiation
GO:0048709 IEA oligodendrocyte differentiation
GO:0050885 IEA neuromuscular process controlling balance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044075 nkx6.2 NK6 homeobox 2 protein_coding Danio_rerio
ENSMUSG00000041309 Nkx6-2 NK6 homeobox 2 protein_coding Mus_musculus

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