C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ADAM metallopeptidase domain 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148848 ADAM12 9606 - 10:126012381-126388455 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368676 ADAM12-002 126041346-126388455 protein_coding
  ENST00000368679 ADAM12-001 126012381-126388455 protein_coding
  ENST00000448723 ADAM12-003 126101148-126388455 protein_coding
  ENST00000467145 ADAM12-004 126049603-126070633 processed_transcript
  ENST00000482291 ADAM12-007 126064695-126067006 processed_transcript
  ENST00000485388 ADAM12-006 126090736-126109788 processed_transcript
  ENST00000494661 ADAM12-005 126135368-126155305 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastHeartKidneyLungMuscleOvaryPlacentaTestisENST00000368676ENST00000368679ENST00000448723
Transcript ID Adipose Bladder Brain Breast Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000368676 N/A N/A N/A N/A N/A 0.102±0.00 0.200±0.00 N/A N/A 118.182±79.45 N/A
ENST00000368679 1.193±0.00 N/A 0.041±0.00 N/A N/A 0.097±0.00 N/A 0.005±0.00 0.248±0.00 N/A 0.811±0.00
ENST00000448723 N/A 0.238±0.00 0.125±0.00 1.995±0.00 0.082±0.01 N/A 1.208±0.00 N/A 3.983±0.00 49.037±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003VS CIL_0003VS_0001 CGP 10:125896539-126388455
CIL_0003VM CIL_0003VM_0001 CGP 10:126012381-126670446

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IPI:IEA protein binding
GO:0005576 IEA extracellular region
GO:0005886 IDA plasma membrane
GO:0006508 IEA proteolysis
GO:0007155 IEA cell adhesion
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007520 TAS myoblast fusion
GO:0008237 TAS metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0016021 IEA integral component of membrane
GO:0017124 IPI SH3 domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079068 adam12 a disintegrin and metalloproteinase domain 12 (meltrin alpha) protein_coding Danio_rerio
ENSMUSG00000054555 Adam12 a disintegrin and metallopeptidase domain 12 (meltrin alpha) protein_coding Mus_musculus

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