C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin and metallopeptidase domain 12 (meltrin alpha)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000054555 Adam12 10090 - 7:133883199-134232146 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000067680 Adam12-001 133883199-134225097 protein_coding
  ENSMUST00000127524 Adam12-003 133981412-134232146 protein_coding
  ENSMUST00000134504 Adam12-004 133975475-134232005 protein_coding
  ENSMUST00000138363 Adam12-005 133886196-133961265 protein_coding
  ENSMUST00000154144 Adam12-002 134191272-134225372 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000067680ENSMUST00000127524ENSMUST00000134504ENSMUST00000138363
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000067680 12.809±7.56 2.639±1.08 1.192±0.10 0.611±0.43 7.535±2.80 0.326±0.05 0.092±0.01 1.399±0.35 0.679±0.42 0.444±0.13 0.037±0.01 7.217±2.19 1.484±0.79 N/A
ENSMUST00000127524 N/A N/A N/A N/A N/A 0.855±0.14 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000134504 N/A N/A N/A N/A N/A 0.808±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000138363 N/A 0.878±0.00 N/A N/A N/A 0.136±0.00 N/A N/A 0.081±0.02 0.210±0.00 N/A 1.643±0.00 N/A 0.049±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003VS CIL_0003VS_0002 CGP 7:133776861-134232146
CIL_0003VM CIL_0003VM_0002 CGP 7:133883199-134385661

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0006508 IEA proteolysis
GO:0007155 IEA cell adhesion
GO:0008270 IEA zinc ion binding
GO:0016021 IEA integral component of membrane
GO:0017124 IEA SH3 domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079068 adam12 a disintegrin and metalloproteinase domain 12 (meltrin alpha) protein_coding Danio_rerio
ENSG00000148848 ADAM12 ADAM metallopeptidase domain 12 protein_coding Homo_sapiens

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