C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000149305 HTR3B 9606 + 11:113904677-113946565 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260191 HTR3B-001 113904677-113946565 protein_coding
  ENST00000537778 HTR3B-002 113908992-113946252 protein_coding
  ENST00000543092 HTR3B-003 113931385-113944702 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeColonKidneyLiverLungMuscleOvaryTestisENST00000260191ENST00000537778ENST00000543092
Transcript ID Adipose Colon Kidney Liver Lung Muscle Ovary Testis
ENST00000260191 0.022±0.00 0.056±0.00 0.052±0.00 0.026±0.00 0.157±0.00 0.006±0.00 0.038±0.02 0.150±0.00
ENST00000537778 N/A N/A N/A N/A N/A N/A N/A 0.134±0.00
ENST00000543092 N/A N/A N/A N/A N/A N/A N/A 0.317±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002C0 CIL_0002C0_0002 CGP 11:113797874-113946565

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004993 IEA serotonin receptor activity
GO:0005216 TAS ion channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005232 IEA serotonin-activated cation-selective channel activity
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006810 TAS:IEA transport
GO:0006811 IEA ion transport
GO:0006812 IEA cation transport
GO:0007210 IEA serotonin receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0034220 TAS ion transmembrane transport
GO:0045211 IEA postsynaptic membrane
GO:0055085 TAS transmembrane transport
GO:0098655 TAS cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061749 htr3b 5-hydroxytryptamine (serotonin) receptor 3B protein_coding Danio_rerio
ENSMUSG00000008590 Htr3b 5-hydroxytryptamine (serotonin) receptor 3B protein_coding Mus_musculus

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