C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: junctophilin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000149596 JPH2 9606 - 20:44111695-44187578 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342272 JPH2-002 44176817-44187093 protein_coding
  ENST00000372980 JPH2-001 44111695-44187578 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000342272ENST00000372980
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000342272 N/A N/A 0.096±0.00 0.205±0.00 N/A N/A 1.856±0.00 0.442±0.00 4.377±0.00 0.332±0.00 5.439±0.00 0.114±0.00 1.291±0.00 N/A
ENST00000372980 2.533±0.00 9.975±0.00 0.015±0.00 0.562±0.52 4.338±1.95 17.943±15.66 29.344±26.10 1.986±0.00 1.339±1.27 2.011±1.62 19.339±5.03 2.806±2.55 7.050±2.74 3.399±2.97

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00044Q CIL_00044Q_0001 CGP 20:43914864-44187578
CIL_00044N CIL_00044N_0001 CGP 20:44111695-44210791

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001786 IDA phosphatidylserine binding
GO:0005515 IPI protein binding
GO:0005546 IDA phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 IDA phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005886 IEA plasma membrane
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0010314 IDA phosphatidylinositol-5-phosphate binding
GO:0014701 TAS junctional sarcoplasmic reticulum membrane
GO:0015278 IDA calcium-release channel activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016529 IEA sarcoplasmic reticulum
GO:0030018 IEA Z disc
GO:0030314 IEA junctional membrane complex
GO:0032266 IDA phosphatidylinositol-3-phosphate binding
GO:0055024 IEA regulation of cardiac muscle tissue development
GO:0055074 IDA calcium ion homeostasis
GO:0060314 TAS regulation of ryanodine-sensitive calcium-release channel activity
GO:0060316 IDA positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0060402 TAS calcium ion transport into cytosol
GO:0070273 IDA phosphatidylinositol-4-phosphate binding
GO:0070300 IDA phosphatidic acid binding
GO:0070588 IDA calcium ion transmembrane transport
GO:0080025 IDA phosphatidylinositol-3,5-bisphosphate binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028625 jph2 junctophilin 2 protein_coding Danio_rerio
ENSMUSG00000017817 Jph2 junctophilin 2 protein_coding Mus_musculus

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