C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: matrix metallopeptidase 3 (stromelysin 1, progelatinase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000149968 MMP3 9606 - 11:102835801-102843803 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000299855 MMP3-001 102835801-102843803 protein_coding
  ENST00000434103 MMP3-002 102836497-102838710 protein_coding
  ENST00000524478 MMP3-003 102842252-102843607 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastLiverLungMuscleOvaryTestisENST00000299855ENST00000434103
Transcript ID Adipose Brain Breast Liver Lung Muscle Ovary Testis
ENST00000299855 3.746±0.00 0.016±0.00 0.235±0.00 0.630±0.00 0.682±0.00 0.111±0.00 2.461±2.34 2.095±0.00
ENST00000434103 N/A 0.128±0.00 2.158±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002MJ CIL_0002MJ_0001 CGP 11:102789920-102843803

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004175 IDA endopeptidase activity
GO:0004222 IEA metalloendopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005576 TAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 TAS extracellular space
GO:0005739 IEA mitochondrion
GO:0005829 IEA cytosol
GO:0006508 IDA:IEA proteolysis
GO:0008237 IEA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0010727 IDA negative regulation of hydrogen peroxide metabolic process
GO:0022617 TAS extracellular matrix disassembly
GO:0030163 IEA protein catabolic process
GO:0030198 TAS extracellular matrix organization
GO:0030334 IEA regulation of cell migration
GO:0030574 TAS collagen catabolic process
GO:0031012 IEA extracellular matrix
GO:0051898 IEA negative regulation of protein kinase B signaling
GO:0071230 IEA cellular response to amino acid stimulus
GO:1903209 ISS positive regulation of oxidative stress-induced cell death

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000043613 Mmp3 matrix metallopeptidase 3 protein_coding Mus_musculus

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