C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CD226 molecule
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000150637 CD226 9606 - 18:69831158-69961803 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000280200 CD226-001 69853275-69956996 protein_coding
  ENST00000577287 CD226-007 69864115-69947419 protein_coding
  ENST00000578928 CD226-008 69831158-69895809 nonsense_mediated_decay
  ENST00000579496 CD226-009 69873144-69961803 protein_coding
  ENST00000580335 CD226-005 69946734-69957176 protein_coding
  ENST00000581982 CD226-003 69862956-69956924 protein_coding
  ENST00000582621 CD226-004 69864314-69947853 protein_coding
  ENST00000583955 CD226-006 69896032-69956670 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBreastColonLiverLungMuscleOvaryTestisENST00000280200ENST00000577287ENST00000581982
Transcript ID Adipose Bladder Breast Colon Liver Lung Muscle Ovary Testis
ENST00000280200 0.025±0.00 0.327±0.00 0.113±0.00 0.398±0.00 0.061±0.00 0.182±0.00 0.003±0.00 0.129±0.00 0.112±0.00
ENST00000577287 N/A N/A 1.134±0.00 N/A N/A N/A N/A N/A N/A
ENST00000581982 N/A N/A N/A N/A 0.262±0.00 1.742±0.00 N/A N/A 0.546±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000AT CIL_0000AT_0002 CGP 18:69401055-69961803
CIL_0000AS CIL_0000AS_0002 CGP 18:69831158-70205945

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001816 IEA cytokine production
GO:0002860 IMP positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0002891 IDA positive regulation of immunoglobulin mediated immune response
GO:0005178 IPI integrin binding
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007155 IEA cell adhesion
GO:0007165 TAS signal transduction
GO:0008037 TAS cell recognition
GO:0009897 IEA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0019901 IPI protein kinase binding
GO:0033005 IDA positive regulation of mast cell activation
GO:0045121 TAS membrane raft
GO:0045954 IMP positive regulation of natural killer cell mediated cytotoxicity
GO:0050776 TAS regulation of immune response
GO:0050839 IPI cell adhesion molecule binding
GO:0060369 IDA positive regulation of Fc receptor mediated stimulatory signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045391 cd226 CD226 molecule protein_coding Danio_rerio
ENSMUSG00000034028 Cd226 CD226 antigen protein_coding Mus_musculus

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