C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CD226 antigen
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034028 Cd226 10090 + 18:89197431-89270201 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037142 Cd226-001 89197431-89270201 protein_coding
  ENSMUST00000097496 Cd226-002 89197498-89269161 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037142ENSMUST00000097496
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037142 0.356±0.07 N/A 0.174±0.12 0.037±0.01 1.755±0.76 0.099±0.05 0.218±0.06 0.080±0.03 0.136±0.05 0.694±0.15 0.031±0.01 0.223±0.12 0.075±0.03 0.016±0.00
ENSMUST00000097496 0.272±0.03 0.303±0.01 N/A 0.064±0.00 N/A N/A 0.114±0.05 0.130±0.05 N/A 0.335±0.00 0.071±0.02 0.198±0.08 0.050±0.00 0.050±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001816 IDA cytokine production
GO:0002860 IEA positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0002891 IEA positive regulation of immunoglobulin mediated immune response
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0007155 IEA cell adhesion
GO:0009897 IDA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0019901 IEA protein kinase binding
GO:0033005 IEA positive regulation of mast cell activation
GO:0045954 IEA positive regulation of natural killer cell mediated cytotoxicity
GO:0050839 IEA cell adhesion molecule binding
GO:0060369 IEA positive regulation of Fc receptor mediated stimulatory signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045391 cd226 CD226 molecule protein_coding Danio_rerio
ENSG00000150637 CD226 CD226 molecule protein_coding Homo_sapiens

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