C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dedicator of cytokinesis 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000150760 DOCK1 9606 + 10:126905409-127452517 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000280333 DOCK1-001 126905409-127452517 protein_coding
  ENST00000464466 DOCK1-004 127248068-127272196 processed_transcript
  ENST00000473861 DOCK1-002 127110245-127128096 retained_intron
  ENST00000484400 DOCK1-003 127248008-127344600 processed_transcript
  ENST00000495574 DOCK1-005 127248025-127257788 retained_intron
  ENST00000623213 DOCK1-006 126905456-127451465 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000280333ENST00000623213
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000280333 14.514±0.00 3.915±0.00 1.984±0.00 5.602±4.49 5.975±4.43 7.047±5.72 4.532±0.00 5.509±5.15 1.217±0.15 5.508±0.00 0.696±0.55 9.059±4.87 7.470±0.24 6.484±4.16
ENST00000623213 N/A N/A 2.138±0.00 1.238±0.00 2.403±0.00 1.967±0.00 0.791±0.00 1.745±0.00 2.218±0.00 2.586±0.77 N/A 4.698±0.82 3.545±0.00 1.665±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00047A CIL_00047A_0002 CGP 10:126424997-127452517
CIL_00047B CIL_00047B_0002 CGP 10:126905409-127452517

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005096 TAS GTPase activator activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006911 TAS phagocytosis, engulfment
GO:0006915 IEA apoptotic process
GO:0007165 TAS signal transduction
GO:0007229 TAS integrin-mediated signaling pathway
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0009055 IEA electron carrier activity
GO:0016020 IEA membrane
GO:0016477 IEA cell migration
GO:0017124 IEA SH3 domain binding
GO:0020037 IEA heme binding
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043547 IEA positive regulation of GTPase activity
GO:0045087 TAS innate immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036012 DOCK1 (1 of 3) dedicator of cytokinesis 1 protein_coding Danio_rerio
ENSDARG00000076059 DOCK1 (2 of 3) dedicator of cytokinesis 1 protein_coding Danio_rerio
ENSDARG00000086908 dock1 dedicator of cytokinesis 1 protein_coding Danio_rerio
ENSMUSG00000058325 Dock1 dedicator of cytokinesis 1 protein_coding Mus_musculus

Loading