C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: discs, large homolog 5 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000151208 DLG5 9606 - 10:77790791-77926526 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000372391 DLG5-001 77790791-77926526 protein_coding
  ENST00000424842 DLG5-005 77790791-77829442 protein_coding
  ENST00000459739 DLG5-003 77793544-77821538 processed_transcript
  ENST00000463362 DLG5-006 77791901-77820048 retained_intron
  ENST00000466198 DLG5-010 77821782-77824730 retained_intron
  ENST00000468332 DLG5-002 77796061-77889507 nonsense_mediated_decay
  ENST00000475613 DLG5-004 77790791-77869191 retained_intron
  ENST00000476354 DLG5-012 77816033-77820021 retained_intron
  ENST00000484525 DLG5-008 77806796-77807977 processed_transcript
  ENST00000489547 DLG5-007 77806105-77812229 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000372391ENST00000424842ENST00000459739ENST00000475613
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000372391 5.159±0.00 1.874±0.00 0.685±0.00 1.723±1.26 3.631±0.20 3.548±2.89 1.174±1.11 1.750±1.48 1.893±1.37 3.473±0.00 8.623±0.00 8.085±4.63 15.441±8.51 9.804±2.41
ENST00000424842 2.680±0.00 1.736±0.00 N/A 1.478±0.98 4.663±0.00 7.327±0.00 0.631±0.00 3.304±0.00 0.431±0.00 1.525±0.00 N/A 8.929±0.00 5.229±0.41 10.398±0.00
ENST00000459739 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.931±0.00 N/A N/A N/A
ENST00000475613 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.634±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004CA CIL_0004CA_0001 CGP 10:76869601-77926526

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005737 TAS cytoplasm
GO:0005886 IEA plasma membrane
GO:0005913 IEA cell-cell adherens junction
GO:0006461 IEA protein complex assembly
GO:0007165 TAS signal transduction
GO:0008013 IDA beta-catenin binding
GO:0008092 IDA cytoskeletal protein binding
GO:0008285 TAS negative regulation of cell proliferation
GO:0016337 NAS single organismal cell-cell adhesion
GO:0030159 NAS receptor signaling complex scaffold activity
GO:0030859 IEA polarized epithelial cell differentiation
GO:0030901 IEA midbrain development
GO:0035556 NAS intracellular signal transduction
GO:0042981 IEA regulation of apoptotic process
GO:0045176 IEA apical protein localization
GO:0045186 IEA zonula adherens assembly
GO:0045197 IEA establishment or maintenance of epithelial cell apical/basal polarity
GO:0060441 IEA epithelial tube branching involved in lung morphogenesis
GO:0071896 IEA protein localization to adherens junction
GO:0072205 IEA metanephric collecting duct development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086014 DLG5 discs, large homolog 5 (Drosophila) protein_coding Danio_rerio
ENSMUSG00000021782 Dlg5 discs, large homolog 5 (Drosophila) protein_coding Mus_musculus

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