C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: discs, large homolog 5 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021782 Dlg5 10090 - 14:24133953-24245920 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042009 Dlg5-003 24133953-24177789 protein_coding
  ENSMUST00000073687 Dlg5-001 24133953-24245920 protein_coding
  ENSMUST00000090398 Dlg5-002 24133955-24245920 protein_coding
  ENSMUST00000164638 Dlg5-008 24146281-24148764 retained_intron
  ENSMUST00000166007 Dlg5-004 24133953-24146188 protein_coding
  ENSMUST00000167343 Dlg5-006 24154308-24157265 retained_intron
  ENSMUST00000169880 Dlg5-005 24190318-24244865 protein_coding
  ENSMUST00000170112 Dlg5-007 24144384-24150546 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000042009ENSMUST00000073687ENSMUST00000090398ENSMUST00000166007ENSMUST00000167343
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000042009 2.973±0.16 4.579±1.72 1.880±0.70 3.212±0.00 1.825±0.45 2.718±0.27 0.303±0.07 1.541±0.28 0.233±0.08 2.297±1.12 0.478±0.21 5.626±2.45 15.711±15.00 0.666±0.00
ENSMUST00000073687 N/A N/A N/A N/A N/A N/A N/A N/A 0.134±0.00 N/A N/A 3.691±0.00 N/A 0.118±0.00
ENSMUST00000090398 3.194±0.98 5.343±2.00 2.107±0.10 4.289±2.00 1.916±0.80 2.915±0.77 0.576±0.25 1.824±0.70 0.298±0.09 2.332±0.50 0.324±0.10 9.179±2.34 4.384±2.22 N/A
ENSMUST00000166007 N/A N/A 3.300±0.00 N/A 2.175±0.00 N/A N/A 2.177±0.13 0.512±0.01 N/A N/A N/A 17.057±0.00 N/A
ENSMUST00000167343 N/A 14.861±1.12 N/A N/A 6.035±0.00 12.226±0.00 N/A N/A N/A N/A N/A 21.814±2.01 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004CA CIL_0004CA_0002 CGP 14:23289431-24245920

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005913 IDA cell-cell adherens junction
GO:0006461 IMP protein complex assembly
GO:0008013 IEA beta-catenin binding
GO:0008092 IEA cytoskeletal protein binding
GO:0030859 IMP polarized epithelial cell differentiation
GO:0030901 IMP midbrain development
GO:0042981 IEA regulation of apoptotic process
GO:0045176 IMP apical protein localization
GO:0045186 IMP zonula adherens assembly
GO:0045197 IMP establishment or maintenance of epithelial cell apical/basal polarity
GO:0060441 IMP epithelial tube branching involved in lung morphogenesis
GO:0071896 IMP protein localization to adherens junction
GO:0072205 IMP metanephric collecting duct development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086014 DLG5 discs, large homolog 5 (Drosophila) protein_coding Danio_rerio
ENSG00000151208 DLG5 discs, large homolog 5 (Drosophila) protein_coding Homo_sapiens

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