C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: malic enzyme 3, NADP(+)-dependent, mitochondrial
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000151376 ME3 9606 - 11:86441108-86672636 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000323418 ME3-201 86464082-86672385 protein_coding
  ENST00000393324 ME3-001 86441108-86672198 protein_coding
  ENST00000524826 ME3-004 86441352-86672636 protein_coding
  ENST00000525957 ME3-011 86457579-86498124 processed_transcript
  ENST00000526504 ME3-002 86449965-86672636 nonsense_mediated_decay
  ENST00000526834 ME3-009 86671760-86672372 protein_coding
  ENST00000526944 ME3-005 86671762-86672613 protein_coding
  ENST00000530335 ME3-007 86556565-86672618 protein_coding
  ENST00000530520 ME3-003 86446893-86671965 retained_intron
  ENST00000532471 ME3-010 86671706-86672428 protein_coding
  ENST00000534638 ME3-008 86667739-86671822 processed_transcript
  ENST00000543262 ME3-202 86441110-86672636 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000393324ENST00000524826ENST00000526504ENST00000530520ENST00000543262
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000393324 1.819±0.00 2.351±0.00 7.231±0.00 5.193±0.00 2.091±0.00 3.624±0.00 2.692±0.00 1.199±0.00 2.625±0.00 3.353±0.00 6.773±3.81 1.492±0.87 2.807±0.22
ENST00000524826 N/A 1.513±0.00 3.340±0.29 4.960±0.00 2.542±0.00 1.179±0.00 2.537±0.00 N/A 1.629±0.00 1.364±0.64 1.902±0.00 1.519±0.87 1.139±0.44
ENST00000526504 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.561±0.00 N/A 2.621±0.00
ENST00000530520 N/A N/A N/A N/A N/A N/A N/A 0.795±0.00 N/A N/A N/A N/A N/A
ENST00000543262 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.432±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004470 IDA malic enzyme activity
GO:0004471 IEA malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0004473 IDA malate dehydrogenase (decarboxylating) (NADP+) activity
GO:0005739 TAS mitochondrion
GO:0006090 IDA pyruvate metabolic process
GO:0006108 IEA malate metabolic process
GO:0008948 IEA oxaloacetate decarboxylase activity
GO:0009060 TAS aerobic respiration
GO:0046872 IEA metal ion binding
GO:0048037 TAS cofactor binding
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0072592 TAS oxygen metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002305 me3 malic enzyme 3, NADP(+)-dependent, mitochondrial protein_coding Danio_rerio
ENSMUSG00000030621 Me3 malic enzyme 3, NADP(+)-dependent, mitochondrial protein_coding Mus_musculus

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