C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: malic enzyme 3, NADP(+)-dependent, mitochondrial
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030621 Me3 10090 + 7:89632392-89854359 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032853 Me3-006 89829282-89851962 protein_coding
  ENSMUST00000032856 Me3-001 89632703-89854359 protein_coding
  ENSMUST00000159167 Me3-002 89632886-89849152 retained_intron
  ENSMUST00000159491 Me3-005 89736731-89818433 processed_transcript
  ENSMUST00000159504 Me3-004 89632392-89810197 retained_intron
  ENSMUST00000160995 Me3-007 89739917-89818931 processed_transcript
  ENSMUST00000162145 Me3-003 89632534-89643673 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032853ENSMUST00000032856ENSMUST00000159167ENSMUST00000159504ENSMUST00000160995ENSMUST00000162145
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032853 2.889±1.71 1.543±0.00 2.458±0.31 9.828±12.94 4.763±3.08 1.179±0.05 16.150±2.86 17.598±1.81 0.043±0.00 1.197±0.23 18.388±1.73 8.689±1.26 N/A 6.309±2.32
ENSMUST00000032856 N/A N/A 0.535±0.00 0.776±0.95 N/A 0.878±0.00 2.209±0.00 N/A N/A N/A N/A 0.737±0.00 N/A N/A
ENSMUST00000159167 1.078±0.61 0.662±0.00 1.092±0.00 3.117±4.09 4.323±0.00 0.475±0.00 N/A N/A 0.085±0.03 0.800±0.00 N/A 4.500±1.13 0.161±0.00 N/A
ENSMUST00000159504 N/A N/A N/A N/A N/A N/A N/A N/A 0.067±0.00 N/A N/A 0.946±0.00 N/A N/A
ENSMUST00000160995 N/A N/A N/A N/A N/A N/A N/A N/A 0.551±0.18 N/A N/A 15.401±0.00 N/A N/A
ENSMUST00000162145 3.016±2.65 N/A 0.481±0.00 0.282±0.00 1.310±0.32 1.965±1.11 N/A 4.725±0.69 0.756±0.61 1.614±0.25 N/A 3.532±0.33 0.415±0.20 0.930±0.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008U2 CIL_0008U2_0002 VISTA 7:89154519-89757634

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004470 ISS malic enzyme activity
GO:0004471 IEA malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0004473 ISS malate dehydrogenase (decarboxylating) (NADP+) activity
GO:0005739 IDA mitochondrion
GO:0006090 ISS pyruvate metabolic process
GO:0006108 IEA malate metabolic process
GO:0008948 IEA oxaloacetate decarboxylase activity
GO:0046872 IEA metal ion binding
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002305 me3 malic enzyme 3, NADP(+)-dependent, mitochondrial protein_coding Danio_rerio
ENSG00000151376 ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial protein_coding Homo_sapiens

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