C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152234 ATP5A1 9606 - 18:46080248-46104334 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282050 ATP5A1-201 46084144-46104233 protein_coding
  ENST00000398752 ATP5A1-001 46080248-46098353 protein_coding
  ENST00000585650 ATP5A1-014 46089959-46099352 nonsense_mediated_decay
  ENST00000586523 ATP5A1-013 46084150-46088696 retained_intron
  ENST00000586592 ATP5A1-008 46084150-46098315 nonsense_mediated_decay
  ENST00000587902 ATP5A1-007 46084427-46086584 retained_intron
  ENST00000588390 ATP5A1-019 46094700-46098295 retained_intron
  ENST00000589252 ATP5A1-018 46087427-46098295 protein_coding
  ENST00000589611 ATP5A1-010 46089429-46092198 retained_intron
  ENST00000589869 ATP5A1-003 46088136-46104334 protein_coding
  ENST00000590156 ATP5A1-002 46084150-46098295 nonsense_mediated_decay
  ENST00000590324 ATP5A1-004 46089632-46104233 protein_coding
  ENST00000590406 ATP5A1-005 46089599-46104227 protein_coding
  ENST00000590448 ATP5A1-022 46089759-46104253 retained_intron
  ENST00000590665 ATP5A1-009 46084150-46098296 protein_coding
  ENST00000591267 ATP5A1-015 46093180-46098296 processed_transcript
  ENST00000591981 ATP5A1-020 46089822-46098296 nonsense_mediated_decay
  ENST00000592364 ATP5A1-021 46086127-46098285 nonsense_mediated_decay
  ENST00000592989 ATP5A1-016 46089822-46104273 protein_coding
  ENST00000593152 ATP5A1-202 46084144-46098353 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000282050ENST00000586592ENST00000589252ENST00000589869ENST00000590406ENST00000590665ENST00000591981
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000282050 95.761±0.00 141.538±0.00 52.565±0.00 121.884±29.43 98.692±72.28 93.930±20.30 319.130±178.13 130.309±86.83 71.972±21.36 34.417±26.38 102.229±29.14 97.538±59.86 153.475±35.09 122.641±26.79
ENST00000586592 N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.205±0.00 N/A N/A N/A N/A
ENST00000589252 N/A N/A N/A 84.389±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000589869 N/A N/A N/A N/A 25.287±0.00 N/A N/A 18.121±0.00 N/A N/A N/A 65.487±0.00 74.571±0.00 120.215±0.00
ENST00000590406 N/A N/A N/A N/A N/A N/A N/A 19.022±0.00 N/A N/A N/A N/A N/A N/A
ENST00000590665 N/A N/A N/A N/A N/A N/A 95.591±0.00 N/A 38.899±0.00 25.093±0.00 43.994±0.00 25.745±0.00 36.366±0.00 N/A
ENST00000591981 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 109.956±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001937 IMP negative regulation of endothelial cell proliferation
GO:0005515 IPI protein binding
GO:0005524 ISS:IEA ATP binding
GO:0005739 NAS mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005753 IDA mitochondrial proton-transporting ATP synthase complex
GO:0005759 TAS mitochondrial matrix
GO:0005886 IDA plasma membrane
GO:0006200 IDA ATP catabolic process
GO:0006629 ISS lipid metabolic process
GO:0006754 IC ATP biosynthetic process
GO:0008180 IDA COP9 signalosome
GO:0009790 ISS embryo development
GO:0015986 IEA ATP synthesis coupled proton transport
GO:0015991 IEA ATP hydrolysis coupled proton transport
GO:0015992 IEA proton transport
GO:0016020 IDA membrane
GO:0016820 IEA hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0016887 IDA ATPase activity
GO:0022857 IC transmembrane transporter activity
GO:0022904 TAS respiratory electron transport chain
GO:0033178 IEA proton-transporting two-sector ATPase complex, catalytic domain
GO:0042288 IDA MHC class I protein binding
GO:0042776 IC mitochondrial ATP synthesis coupled proton transport
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045261 IEA proton-transporting ATP synthase complex, catalytic core F(1)
GO:0046034 IEA ATP metabolic process
GO:0046933 ISS:IEA proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 IEA proton-transporting ATPase activity, rotational mechanism
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010149 atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle protein_coding Danio_rerio
ENSMUSG00000025428 Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 protein_coding Mus_musculus

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