C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025428 Atp5a1 10090 + 18:77773729-77782869 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026495 Atp5a1-001 77773729-77782869 protein_coding
  ENSMUST00000114748 Atp5a1-002 77773956-77782866 protein_coding
  ENSMUST00000128073 Atp5a1-004 77778955-77781099 retained_intron
  ENSMUST00000135678 Atp5a1-003 77773992-77782655 nonsense_mediated_decay
  ENSMUST00000146869 Atp5a1-005 77779832-77781889 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026495ENSMUST00000114748ENSMUST00000128073
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026495 271.426±28.32 179.404±34.84 341.311±72.08 227.311±29.55 257.621±47.95 288.820±44.09 1409.538±48.73 588.313±48.92 366.480±86.04 140.953±16.88 626.926±166.47 287.727±100.47 210.616±130.44 67.465±20.09
ENSMUST00000114748 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 255.309±83.73 N/A 146.803±88.94 37.863±0.00
ENSMUST00000128073 N/A 560.465±152.48 N/A N/A 350.076±123.21 510.693±191.54 1072.220±18.98 374.988±0.00 331.198±90.42 75.776±0.00 N/A 363.010±115.11 N/A 65.735±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001P6 CIL_0001P6_0002 CGP 18:77757567-77782869

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001937 IEA negative regulation of endothelial cell proliferation
GO:0005515 IEA protein binding
GO:0005524 IMP ATP binding
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005753 ISS mitochondrial proton-transporting ATP synthase complex
GO:0005886 IEA plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006629 IMP lipid metabolic process
GO:0008180 IEA COP9 signalosome
GO:0015986 IEA ATP synthesis coupled proton transport
GO:0015991 IEA ATP hydrolysis coupled proton transport
GO:0016020 IEA membrane
GO:0016887 IEA ATPase activity
GO:0042288 IEA MHC class I protein binding
GO:0044822 IEA poly(A) RNA binding
GO:0045261 IEA proton-transporting ATP synthase complex, catalytic core F(1)
GO:0046933 IMP proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 IEA proton-transporting ATPase activity, rotational mechanism
GO:0070062 IEA extracellular vesicular exosome
GO:1902600 IMP hydrogen ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010149 atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle protein_coding Danio_rerio
ENSG00000152234 ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle protein_coding Homo_sapiens

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