C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, metabotropic 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152822 GRM1 9606 + 6:146027646-146437598 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282753 GRM1-001 146029283-146437598 protein_coding
  ENST00000355289 GRM1-019 146029283-146434885 protein_coding
  ENST00000361719 GRM1-201 146027782-146437598 protein_coding
  ENST00000492807 GRM1-002 146027782-146437595 protein_coding
  ENST00000502405 GRM1-018 146027703-146159891 retained_intron
  ENST00000507005 GRM1-017 146027646-146159692 retained_intron
  ENST00000507907 GRM1-020 146029486-146434885 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000282753ENST00000355289ENST00000492807ENST00000507005ENST00000507907
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000282753 0.006±0.00 0.033±0.00 0.429±0.00 1.683±0.00 0.026±0.00 0.036±0.03 0.431±0.00 0.439±0.00 0.013±0.00 0.013±0.01 N/A 0.018±0.01 0.047±0.03 0.128±0.00
ENST00000355289 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.012±0.00 0.009±0.00 0.069±0.00
ENST00000492807 N/A N/A N/A 2.384±0.00 N/A N/A 0.395±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000507005 0.031±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.014±0.00 0.149±0.10 N/A 0.190±0.00
ENST00000507907 N/A N/A 0.111±0.00 2.731±0.00 0.093±0.00 N/A N/A N/A N/A N/A N/A N/A 0.008±0.00 0.288±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0000187 IEA activation of MAPK activity
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005886 TAS plasma membrane
GO:0005887 IBA integral component of plasma membrane
GO:0007186 IDA:IEA G-protein coupled receptor signaling pathway
GO:0007205 IBA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007216 IBA G-protein coupled glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007626 IEA locomotory behavior
GO:0008066 IDA glutamate receptor activity
GO:0008219 IEA cell death
GO:0014069 IBA postsynaptic density
GO:0016021 IEA integral component of membrane
GO:0019233 IEA sensory perception of pain
GO:0030425 IEA dendrite
GO:0038037 IDA G-protein coupled receptor dimeric complex
GO:0038038 IPI G-protein coupled receptor homodimeric complex
GO:0038042 IDA dimeric G-protein coupled receptor signaling pathway
GO:0043005 IEA neuron projection
GO:0043408 IEA regulation of MAPK cascade
GO:0051482 IMP positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0051930 IEA regulation of sensory perception of pain
GO:0051966 IBA regulation of synaptic transmission, glutamatergic
GO:0071257 IEA cellular response to electrical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026796 grm1a glutamate receptor, metabotropic 1a protein_coding Danio_rerio
ENSDARG00000041162 GRM1 (2 of 2) glutamate receptor, metabotropic 1 protein_coding Danio_rerio
ENSMUSG00000019828 Grm1 glutamate receptor, metabotropic 1 protein_coding Mus_musculus

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