C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, metabotropic 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019828 Grm1 10090 - 10:10686059-11082356 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044306 Grm1-002 10686059-11082356 protein_coding
  ENSMUST00000105560 Grm1-006 10688801-11080956 protein_coding
  ENSMUST00000105561 Grm1-001 10688588-11082305 protein_coding
  ENSMUST00000135120 Grm1-003 10746182-10748808 processed_transcript
  ENSMUST00000155772 Grm1-004 10689448-10719251 processed_transcript
  ENSMUST00000156826 Grm1-005 11080489-11082250 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044306ENSMUST00000105560ENSMUST00000105561ENSMUST00000135120ENSMUST00000155772
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044306 N/A N/A N/A 0.588±0.25 0.022±0.02 N/A N/A N/A 0.005±0.00 N/A 0.032±0.01 0.008±0.00 0.009±0.01 N/A
ENSMUST00000105560 N/A N/A N/A 4.191±0.00 N/A 0.015±0.01 1.277±0.04 N/A 0.005±0.00 0.004±0.00 0.015±0.00 0.016±0.01 0.042±0.00 N/A
ENSMUST00000105561 0.012±0.00 0.034±0.00 0.005±0.00 N/A N/A 0.013±0.01 N/A 0.006±0.00 0.006±0.01 0.009±0.01 0.030±0.00 0.035±0.03 0.032±0.02 2.729±0.00
ENSMUST00000135120 N/A N/A N/A N/A 0.117±0.02 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000155772 N/A 0.127±0.00 N/A N/A N/A 0.185±0.07 N/A 0.097±0.04 N/A N/A N/A 0.244±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IDA activation of MAPKK activity
GO:0000187 IDA activation of MAPK activity
GO:0001639 TAS PLC activating G-protein coupled glutamate receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005887 ISS integral component of plasma membrane
GO:0007186 ISS G-protein coupled receptor signaling pathway
GO:0007205 IBA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007206 TAS phospholipase C-activating G-protein coupled glutamate receptor signaling pathway
GO:0007216 ISS G-protein coupled glutamate receptor signaling pathway
GO:0007626 IMP locomotory behavior
GO:0008066 ISS glutamate receptor activity
GO:0014069 IDA postsynaptic density
GO:0019233 IMP sensory perception of pain
GO:0030425 IDA dendrite
GO:0038037 IEA G-protein coupled receptor dimeric complex
GO:0038038 IEA G-protein coupled receptor homodimeric complex
GO:0038042 ISS dimeric G-protein coupled receptor signaling pathway
GO:0043005 IDA neuron projection
GO:0043025 TAS neuronal cell body
GO:0043408 IDA regulation of MAPK cascade
GO:0045211 TAS postsynaptic membrane
GO:0051482 ISS positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0051930 IDA regulation of sensory perception of pain
GO:0051966 IBA regulation of synaptic transmission, glutamatergic
GO:0071257 IMP cellular response to electrical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026796 grm1a glutamate receptor, metabotropic 1a protein_coding Danio_rerio
ENSDARG00000041162 GRM1 (2 of 2) glutamate receptor, metabotropic 1 protein_coding Danio_rerio
ENSG00000152822 GRM1 glutamate receptor, metabotropic 1 protein_coding Homo_sapiens

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