C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class I-related
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000153029 MR1 9606 + 1:181033425-181061938 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282990 MR1-002 181034003-181056553 protein_coding
  ENST00000367578 MR1-004 181034022-181051273 retained_intron
  ENST00000367579 MR1-003 181034003-181055523 protein_coding
  ENST00000367580 MR1-001 181034003-181061938 protein_coding
  ENST00000434571 MR1-201 181033425-181061938 protein_coding
  ENST00000438435 MR1-005 181034010-181055284 processed_transcript
  ENST00000486453 MR1-006 181033972-181049697 retained_intron
  ENST00000614012 MR1-202 181033425-181061938 protein_coding
  ENST00000617803 MR1-203 181033425-181061938 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000282990ENST00000367578ENST00000367579ENST00000367580ENST00000434571ENST00000438435ENST00000614012ENST00000617803
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000282990 1.116±0.00 N/A 0.595±0.00 0.674±0.00 1.202±0.16 1.405±0.00 0.456±0.10 1.417±0.75 1.218±0.73 2.309±0.49 0.362±0.00 2.618±0.70 5.238±0.82 1.164±0.00
ENST00000367578 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.341±0.00
ENST00000367579 N/A N/A N/A N/A N/A N/A N/A N/A 1.035±0.00 N/A N/A N/A 3.088±0.22 N/A
ENST00000367580 0.852±0.00 N/A 0.353±0.00 0.659±0.00 0.325±0.00 0.510±0.15 0.542±0.00 1.615±0.88 0.700±0.47 1.283±0.74 N/A 1.462±0.55 1.284±0.14 0.772±0.49
ENST00000434571 N/A 0.660±0.00 N/A 0.258±0.00 N/A N/A N/A N/A 0.262±0.00 0.655±0.00 0.161±0.00 N/A N/A 0.092±0.00
ENST00000438435 N/A N/A 2.573±0.00 0.838±0.00 3.269±0.00 2.352±0.00 0.523±0.00 N/A 4.278±0.00 3.857±0.00 N/A 5.150±0.00 N/A N/A
ENST00000614012 N/A N/A N/A N/A 0.842±0.00 N/A N/A N/A N/A N/A N/A 1.116±0.00 N/A N/A
ENST00000617803 0.812±0.00 2.120±0.00 0.341±0.00 0.375±0.00 1.101±0.00 0.503±0.00 0.169±0.00 N/A N/A N/A 0.470±0.00 2.147±0.00 0.392±0.00 0.591±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007W1 CIL_0007W1_0001 VISTA 1:180851913-181454518

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002367 IEA cytokine production involved in immune response
GO:0002474 IEA antigen processing and presentation of peptide antigen via MHC class I
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0005783 IDA endoplasmic reticulum
GO:0006955 TAS:IEA immune response
GO:0007165 TAS signal transduction
GO:0016021 IEA integral component of membrane
GO:0019882 IEA antigen processing and presentation
GO:0032393 TAS MHC class I receptor activity
GO:0032611 IEA interleukin-1 beta production
GO:0032620 IEA interleukin-17 production
GO:0042605 IEA peptide antigen binding
GO:0042612 IEA MHC class I protein complex
GO:0045087 IEA innate immune response
GO:0050829 IEA defense response to Gram-negative bacterium

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000026471 Mr1 major histocompatibility complex, class I-related protein_coding Mus_musculus

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