C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CD8a molecule
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000153563 CD8A 9606 - 2:86784610-86808396 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000283635 CD8A-001 86784610-86791680 protein_coding
  ENST00000352580 CD8A-002 86784610-86790895 protein_coding
  ENST00000409511 CD8A-006 86784611-86808396 protein_coding
  ENST00000409781 CD8A-004 86785920-86790825 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000283635ENST00000352580ENST00000409511ENST00000409781
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000283635 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.112±0.00
ENST00000352580 0.399±0.00 21.367±0.00 0.608±0.05 0.658±0.27 0.395±0.04 0.518±0.00 0.286±0.14 1.169±0.16 4.907±3.27 N/A 0.672±0.29 0.980±0.70 0.473±0.33
ENST00000409511 N/A N/A 0.214±0.09 0.556±0.39 0.270±0.00 N/A N/A N/A N/A 0.053±0.00 1.334±0.00 N/A 0.235±0.02
ENST00000409781 N/A N/A N/A N/A 1.317±0.00 N/A N/A 1.146±0.00 N/A 0.118±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002456 IEA T cell mediated immunity
GO:0005515 IPI:IEA protein binding
GO:0005576 IEA extracellular region
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006955 NAS immune response
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007169 NAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0009897 IDA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0015026 NAS coreceptor activity
GO:0016020 IEA membrane
GO:0019882 NAS antigen processing and presentation
GO:0019901 IEA protein kinase binding
GO:0042101 NAS T cell receptor complex
GO:0042110 NAS T cell activation
GO:0042288 NAS MHC class I protein binding
GO:0042803 IEA protein homodimerization activity
GO:0045065 IEA cytotoxic T cell differentiation
GO:0050776 TAS regulation of immune response
GO:0050850 IEA positive regulation of calcium-mediated signaling
GO:0051607 IEA defense response to virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000053977 Cd8a CD8 antigen, alpha chain protein_coding Mus_musculus

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