C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CD8 antigen, alpha chain
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053977 Cd8a 10090 + 6:71373427-71379171 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066747 Cd8a-201 71373427-71379171 protein_coding
  ENSMUST00000172321 Cd8a-202 71373427-71379171 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066747ENSMUST00000172321
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066747 0.149±0.06 0.032±0.00 0.061±0.03 N/A 8.456±4.35 0.262±0.11 0.069±0.04 0.847±0.31 0.066±0.05 0.830±0.36 0.436±0.43 0.073±0.07 0.018±0.02 0.005±0.00
ENSMUST00000172321 0.068±0.00 0.128±0.06 0.055±0.01 0.015±0.01 4.768±2.43 0.214±0.16 0.098±0.02 0.510±0.28 0.064±0.05 0.228±0.06 0.009±0.00 0.075±0.06 0.032±0.02 0.020±0.01

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002456 IMP T cell mediated immunity
GO:0005515 IPI protein binding
GO:0007166 IDA cell surface receptor signaling pathway
GO:0009897 IDA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0016021 IEA integral component of membrane
GO:0019901 IEA protein kinase binding
GO:0042110 IEA T cell activation
GO:0042803 IDA protein homodimerization activity
GO:0045065 IMP cytotoxic T cell differentiation
GO:0050850 IDA positive regulation of calcium-mediated signaling
GO:0051607 IDA defense response to virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000153563 CD8A CD8a molecule protein_coding Homo_sapiens

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