C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BUB3 mitotic checkpoint protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154473 BUB3 9606 + 10:123154277-123170467 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368858 BUB3-002 123154415-123165365 protein_coding
  ENST00000368859 BUB3-004 123154402-123165212 protein_coding
  ENST00000368865 BUB3-001 123154277-123170467 protein_coding
  ENST00000407911 BUB3-005 123154859-123162693 protein_coding
  ENST00000481952 BUB3-006 123162254-123163241 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368858ENST00000368865ENST00000407911ENST00000481952
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368858 13.436±0.00 20.594±0.00 N/A 9.615±5.06 8.361±4.76 9.476±6.07 8.212±0.00 11.929±8.85 4.910±2.60 7.533±3.51 10.978±0.00 18.295±8.24 15.981±1.92 25.144±9.91
ENST00000368865 1.937±0.00 N/A 0.412±0.00 1.853±1.55 1.804±0.27 1.500±0.29 0.928±0.00 1.456±1.14 0.315±0.00 N/A 0.577±0.45 3.576±2.35 1.730±0.45 2.370±0.05
ENST00000407911 N/A N/A 2.208±0.00 N/A N/A N/A N/A N/A N/A 7.536±0.00 3.272±0.00 13.819±0.00 N/A 21.597±0.00
ENST00000481952 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.744±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008DB CIL_0008DB_0001 VISTA 10:122767938-123370218
CIL_0009A3 CIL_0009A3_0001 VISTA 10:122792297-123393555
CIL_0007QE CIL_0007QE_0001 VISTA 10:122843411-123445122
CIL_00099C CIL_00099C_0001 VISTA 10:123048803-123649878
CIL_0007LX CIL_0007LX_0001 UCNEbase 10:123069326-123458100
CIL_0008SI CIL_0008SI_0001 VISTA 10:123129471-123730559
CIL_00011T CIL_00011T_0001 CGP 10:123148122-123170467
CIL_00011U CIL_00011U_0001 CGP 10:123154277-123694607

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000070 IEA mitotic sister chromatid segregation
GO:0000278 TAS mitotic cell cycle
GO:0000776 IDA kinetochore
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0007059 IEA chromosome segregation
GO:0007094 TAS mitotic spindle assembly checkpoint
GO:0008608 IDA attachment of spindle microtubules to kinetochore
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0051321 IEA meiotic cell cycle
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051983 IEA regulation of chromosome segregation
GO:0071173 IDA spindle assembly checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075883 bub3 BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) protein_coding Danio_rerio
ENSMUSG00000066979 Bub3 budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) protein_coding Mus_musculus

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