C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ADAM metallopeptidase with thrombospondin type 1 motif, 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154736 ADAMTS5 9606 - 21:26917912-26966513 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000284987 ADAMTS5-001 26917912-26966513 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000284987
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000284987 15.687±0.00 1.289±0.00 0.733±0.00 0.098±0.00 4.730±3.58 2.039±1.12 0.961±0.63 0.689±0.29 0.063±0.00 0.450±0.22 0.928±0.44 2.450±1.54 5.146±1.28 1.279±1.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008UA CIL_0008UA_0001 VISTA 21:26654008-27255434
CIL_00032M CIL_00032M_0001 CGP 21:26835747-26966513
CIL_0001QT CIL_0001QT_0001 CGP 21:26917912-28885371

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005178 TAS integrin binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0006508 IEA proteolysis
GO:0008237 TAS metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0031012 IEA extracellular matrix
GO:0042742 IEA defense response to bacterium

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000022894 Adamts5 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) protein_coding Mus_musculus

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