C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022894 Adamts5 10090 - 16:85858170-85901125 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023611 Adamts5-201 85858170-85901125 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023611
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023611 25.799±14.42 3.936±1.46 3.046±0.07 0.403±0.16 15.173±5.83 0.895±0.18 2.591±0.35 5.139±0.69 0.297±0.12 2.784±0.14 1.306±0.27 5.520±2.62 1.021±0.43 0.587±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008UA CIL_0008UA_0002 VISTA 16:85587133-86188622
CIL_00032M CIL_00032M_0002 CGP 16:85793827-85901125
CIL_0001QT CIL_0001QT_0002 CGP 16:85858170-87368742

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IEA protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0006508 IEA proteolysis
GO:0008237 ISO metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0042742 IGI defense response to bacterium

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000154736 ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 protein_coding Homo_sapiens

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