C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth differentiation factor 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000156466 GDF6 9606 - 8:96142330-96160792 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000287020 GDF6-001 96142330-96160792 protein_coding
  ENST00000620978 GDF6-201 96144525-96160719 protein_coding
  ENST00000621429 GDF6-202 96144525-96160716 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000287020ENST00000620978ENST00000621429
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000287020 N/A 0.129±0.12 N/A 0.277±0.00 0.129±0.00 0.134±0.00 0.108±0.00 0.016±0.00 0.027±0.00 0.013±0.00 3.392±0.00 0.503±0.38
ENST00000620978 0.162±0.00 N/A 0.178±0.00 N/A N/A N/A 0.923±0.00 0.039±0.00 N/A N/A N/A N/A
ENST00000621429 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.082±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005125 IEA cytokine activity
GO:0005615 IEA extracellular space
GO:0006915 ISS apoptotic process
GO:0008083 IEA growth factor activity
GO:0010862 IDA positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0030509 IDA BMP signaling pathway
GO:0032924 IDA activin receptor signaling pathway
GO:0040007 IEA growth
GO:0042803 IEA protein homodimerization activity
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0060389 IDA pathway-restricted SMAD protein phosphorylation
GO:1990009 ISS retinal cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005510 gdf6b growth differentiation factor 6b protein_coding Danio_rerio
ENSDARG00000053479 gdf6a growth differentiation factor 6a protein_coding Danio_rerio
ENSMUSG00000051279 Gdf6 growth differentiation factor 6 protein_coding Mus_musculus

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