C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ghrelin/obestatin prepropeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157017 GHRL 9606 - 3:10285675-10292947 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000287656 GHRL-008 10285754-10292917 protein_coding
  ENST00000335542 GHRL-001 10285675-10292947 protein_coding
  ENST00000422159 GHRL-002 10285751-10290212 protein_coding
  ENST00000425479 GHRL-014 10290080-10292938 protein_coding
  ENST00000429122 GHRL-005 10285754-10292933 protein_coding
  ENST00000430179 GHRL-006 10285750-10292917 protein_coding
  ENST00000437422 GHRL-004 10285754-10292917 protein_coding
  ENST00000439975 GHRL-018 10285754-10292917 protein_coding
  ENST00000446937 GHRL-017 10285754-10292917 protein_coding
  ENST00000449238 GHRL-003 10285754-10292917 protein_coding
  ENST00000457360 GHRL-009 10285754-10292917 protein_coding
  ENST00000475759 GHRL-012 10285813-10289807 processed_transcript
  ENST00000476283 GHRL-013 10285813-10289807 processed_transcript
  ENST00000481287 GHRL-015 10285750-10290357 retained_intron
  ENST00000491589 GHRL-016 10285750-10290914 processed_transcript

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00064Z CIL_00064Z_0001 CGP 3:10249372-10292947
CIL_00064V CIL_00064V_0001 CGP 3:10285675-10321178

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IMP activation of MAPK activity
GO:0001664 ISS G-protein coupled receptor binding
GO:0001696 IEA gastric acid secretion
GO:0001937 IDA negative regulation of endothelial cell proliferation
GO:0005179 IEA hormone activity
GO:0005576 IEA:IDA extracellular region
GO:0005615 IDA extracellular space
GO:0005737 IEA cytoplasm
GO:0005788 TAS endoplasmic reticulum lumen
GO:0006006 NAS glucose metabolic process
GO:0007186 ISS G-protein coupled receptor signaling pathway
GO:0007204 ISS positive regulation of cytosolic calcium ion concentration
GO:0008154 IDA actin polymerization or depolymerization
GO:0008343 ISS adult feeding behavior
GO:0009725 IDA response to hormone
GO:0009755 TAS hormone-mediated signaling pathway
GO:0016358 IDA dendrite development
GO:0016525 NAS negative regulation of angiogenesis
GO:0016608 ISS growth hormone-releasing hormone activity
GO:0030252 TAS growth hormone secretion
GO:0030296 IMP protein tyrosine kinase activator activity
GO:0030424 IDA axon
GO:0031768 ISS ghrelin receptor binding
GO:0032024 ISS positive regulation of insulin secretion
GO:0032095 IEA regulation of response to food
GO:0032097 IEA positive regulation of response to food
GO:0032100 ISS positive regulation of appetite
GO:0032691 IDA negative regulation of interleukin-1 beta production
GO:0034774 TAS secretory granule lumen
GO:0040013 IEA negative regulation of locomotion
GO:0040018 IC positive regulation of multicellular organism growth
GO:0042127 IDA regulation of cell proliferation
GO:0042322 IDA negative regulation of circadian sleep/wake cycle, REM sleep
GO:0042536 IDA negative regulation of tumor necrosis factor biosynthetic process
GO:0043066 IDA negative regulation of apoptotic process
GO:0043400 NAS cortisol secretion
GO:0043627 IDA response to estrogen
GO:0044267 TAS cellular protein metabolic process
GO:0045409 IDA negative regulation of interleukin-6 biosynthetic process
GO:0046010 IDA positive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046676 IEA negative regulation of insulin secretion
GO:0046697 IDA decidualization
GO:0050728 IDA negative regulation of inflammatory response
GO:0051216 NAS cartilage development
GO:0051461 IDA positive regulation of corticotropin secretion
GO:0051464 IDA positive regulation of cortisol secretion
GO:0051965 IDA positive regulation of synapse assembly
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0060124 IDA positive regulation of growth hormone secretion
GO:0060399 IC positive regulation of growth hormone receptor signaling pathway
GO:0061098 IMP positive regulation of protein tyrosine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000064177 Ghrl ghrelin protein_coding Mus_musculus

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