C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement component 8, alpha polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157131 C8A 9606 + 1:56854806-56918221 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361249 C8A-001 56854806-56918221 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonKidneyLiverLungTestisENST00000361249
Transcript ID Brain Breast Colon Kidney Liver Lung Testis
ENST00000361249 0.013±0.00 0.141±0.00 0.005±0.00 31.296±31.13 21.691±21.49 0.025±0.00 0.005±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00005D CIL_00005D_0002 CGP 1:56854806-56966140

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001848 IEA complement binding
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005579 IDA membrane attack complex
GO:0005615 TAS extracellular space
GO:0006955 TAS immune response
GO:0006956 IDA complement activation
GO:0006957 IEA complement activation, alternative pathway
GO:0006958 IEA complement activation, classical pathway
GO:0016020 TAS membrane
GO:0019835 IEA cytolysis
GO:0030449 TAS regulation of complement activation
GO:0032403 IEA protein complex binding
GO:0045087 TAS innate immune response
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039516 c8a complement component 8, alpha polypeptide protein_coding Danio_rerio
ENSMUSG00000035031 C8a complement component 8, alpha polypeptide protein_coding Mus_musculus

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