C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement component 8, alpha polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035031 C8a 10090 - 4:104815679-104876398 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000048947 C8a-002 104815679-104876398 protein_coding
  ENSMUST00000064873 C8a-001 104815683-104876383 protein_coding
  ENSMUST00000106808 C8a-003 104815679-104876395 protein_coding
  ENSMUST00000152146 C8a-004 104815679-104856523 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000048947ENSMUST00000064873ENSMUST00000106808ENSMUST00000152146
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000048947 0.031±0.01 N/A 0.034±0.01 0.188±0.00 0.042±0.00 N/A N/A N/A 0.042±0.02 0.026±0.00 N/A 0.029±0.01 0.195±0.03
ENSMUST00000064873 N/A N/A N/A 0.238±0.03 N/A N/A 5.679±1.69 25.233±17.28 N/A N/A N/A 0.057±0.02 N/A
ENSMUST00000106808 N/A 0.004±0.00 0.012±0.00 0.092±0.05 N/A 0.008±0.00 1.435±0.72 7.440±3.54 N/A 0.010±0.00 0.065±0.02 0.042±0.02 0.133±0.00
ENSMUST00000152146 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.204±0.10 0.042±0.02 0.225±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001848 IEA complement binding
GO:0005576 IEA extracellular region
GO:0005579 IEA membrane attack complex
GO:0005615 IEA extracellular space
GO:0006955 IEA immune response
GO:0006956 IEA complement activation
GO:0006957 IEA complement activation, alternative pathway
GO:0006958 IEA complement activation, classical pathway
GO:0019835 IEA cytolysis
GO:0032403 IEA protein complex binding
GO:0070062 IEA extracellular vesicular exosome
GO:0072562 IEA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039516 c8a complement component 8, alpha polypeptide protein_coding Danio_rerio
ENSG00000157131 C8A complement component 8, alpha polypeptide protein_coding Homo_sapiens

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