C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tripartite motif containing 63, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000158022 TRIM63 9606 - 1:26051304-26068436 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374272 TRIM63-001 26051304-26067633 protein_coding
  ENST00000483052 TRIM63-002 26061244-26068436 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374272ENST00000483052
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374272 0.114±0.00 0.089±0.00 0.043±0.00 3.487±2.99 0.190±0.00 62.012±51.91 0.262±0.24 0.604±0.60 0.243±0.20 377.187±329.89 0.057±0.05 1.935±0.41 2.008±1.73
ENST00000483052 N/A 0.018±0.00 0.056±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0004871 NAS signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 NAS cytoplasm
GO:0005874 NAS microtubule
GO:0006936 IEA muscle contraction
GO:0007165 NAS signal transduction
GO:0008270 IEA zinc ion binding
GO:0010468 IEA regulation of gene expression
GO:0014732 IEA skeletal muscle atrophy
GO:0014878 ISS response to electrical stimulus involved in regulation of muscle adaptation
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031432 IDA titin binding
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043292 IEA contractile fiber
GO:0046872 IEA metal ion binding
GO:0051384 IEA response to glucocorticoid
GO:0070555 IEA response to interleukin-1
GO:0071549 IEA cellular response to dexamethasone stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028027 trim63 tripartite motif containing 63 protein_coding Danio_rerio
ENSDARG00000086685 tripartite motif containing 63, E3 ubiquitin protein ligase protein_coding Danio_rerio
ENSMUSG00000028834 Trim63 tripartite motif-containing 63 protein_coding Mus_musculus

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