C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nucleophosmin/nucleoplasmin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000158806 NPM2 9606 + 8:22024125-22036897 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000289820 NPM2-004 22024843-22036897 protein_coding
  ENST00000381530 NPM2-005 22024851-22036897 protein_coding
  ENST00000397940 NPM2-001 22024134-22036896 protein_coding
  ENST00000518119 NPM2-003 22024434-22036897 protein_coding
  ENST00000519373 NPM2-012 22034219-22036896 retained_intron
  ENST00000520125 NPM2-007 22024125-22033156 protein_coding
  ENST00000520180 NPM2-008 22024760-22034148 processed_transcript
  ENST00000520456 NPM2-006 22034108-22036897 retained_intron
  ENST00000521157 NPM2-002 22024125-22036863 protein_coding
  ENST00000522813 NPM2-009 22024137-22034155 protein_coding
  ENST00000522953 NPM2-011 22033101-22036540 retained_intron
  ENST00000524322 NPM2-010 22036491-22036779 retained_intron
  ENST00000615914 NPM2-201 22025249-22036504 protein_coding
  ENST00000621538 NPM2-202 22025249-22036682 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000289820ENST00000381530ENST00000397940ENST00000518119ENST00000519373ENST00000520125ENST00000520180ENST00000520456ENST00000521157ENST00000522813ENST00000522953ENST00000524322ENST00000615914ENST00000621538
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000289820 N/A 0.231±0.00 N/A 6.512±0.00 N/A N/A N/A N/A N/A N/A 0.554±0.00 0.251±0.14 N/A
ENST00000381530 N/A N/A N/A N/A 0.756±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000397940 N/A N/A N/A 4.354±3.34 N/A N/A N/A N/A 0.067±0.05 N/A 0.572±0.33 N/A N/A
ENST00000518119 N/A N/A N/A 7.654±0.00 N/A N/A N/A 0.803±0.00 N/A N/A 1.099±0.00 N/A 0.480±0.00
ENST00000519373 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.583±0.00 N/A N/A N/A
ENST00000520125 N/A N/A N/A N/A N/A N/A N/A N/A 0.407±0.00 N/A N/A 0.332±0.00 N/A
ENST00000520180 N/A N/A N/A N/A 1.073±0.00 N/A N/A N/A 0.112±0.00 1.197±0.00 N/A 0.596±0.00 N/A
ENST00000520456 0.101±0.00 1.255±0.00 N/A 5.293±3.24 0.280±0.00 N/A 0.462±0.00 1.473±0.00 N/A N/A 0.888±0.19 0.257±0.06 1.693±0.56
ENST00000521157 N/A N/A N/A N/A 0.052±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000522813 N/A 0.391±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 3.634±0.00 0.351±0.22 3.192±0.00
ENST00000522953 N/A N/A 0.146±0.00 N/A N/A N/A 0.319±0.00 N/A N/A 0.386±0.13 N/A 0.236±0.00 2.640±0.00
ENST00000524322 0.345±0.00 N/A N/A N/A 1.123±0.00 0.479±0.00 0.546±0.00 4.090±0.00 N/A 1.766±0.00 N/A N/A N/A
ENST00000615914 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.344±0.00 N/A N/A
ENST00000621538 N/A N/A N/A N/A N/A N/A N/A 0.667±0.00 N/A N/A 1.234±0.53 0.154±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000810 CIL_000810_0001 VISTA 8:21687877-22288944
CIL_0008ZI CIL_0008ZI_0001 VISTA 8:21743578-22344815
CIL_000812 CIL_000812_0001 VISTA 8:21749915-22350771

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000789 IDA cytoplasmic chromatin
GO:0000790 IDA nuclear chromatin
GO:0003676 IEA nucleic acid binding
GO:0003682 IEA chromatin binding
GO:0005634 IDA nucleus
GO:0006338 IDA chromatin remodeling
GO:0007096 IMP regulation of exit from mitosis
GO:0007338 IMP single fertilization
GO:0009790 IMP embryo development
GO:0009994 IEP oocyte differentiation
GO:0019899 IEA enzyme binding
GO:0042393 TAS histone binding
GO:0043085 IEA positive regulation of catalytic activity
GO:0045740 IEA positive regulation of DNA replication
GO:0045836 IMP positive regulation of meiosis
GO:0051054 IEA positive regulation of DNA metabolic process
GO:0051260 IEA protein homooligomerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053963 npm2b nucleophosmin/nucleoplasmin, 2b protein_coding Danio_rerio
ENSMUSG00000047911 Npm2 nucleophosmin/nucleoplasmin 2 protein_coding Mus_musculus

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