C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cell cycle and apoptosis regulator 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000158941 CCAR2 9606 + 8:22604632-22621514 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000308511 CCAR2-001 22604632-22621514 protein_coding
  ENST00000389279 CCAR2-002 22605038-22620471 protein_coding
  ENST00000518989 CCAR2-004 22606600-22608077 protein_coding
  ENST00000520536 CCAR2-015 22618157-22620964 retained_intron
  ENST00000520738 CCAR2-009 22614388-22620468 protein_coding
  ENST00000520861 CCAR2-003 22606908-22620468 protein_coding
  ENST00000521020 CCAR2-018 22613885-22614573 retained_intron
  ENST00000521301 CCAR2-011 22604791-22606703 protein_coding
  ENST00000521436 CCAR2-010 22617388-22620468 retained_intron
  ENST00000521837 CCAR2-005 22605500-22607289 protein_coding
  ENST00000522599 CCAR2-013 22612703-22615596 protein_coding
  ENST00000523349 CCAR2-006 22605719-22607325 protein_coding
  ENST00000523801 CCAR2-007 22604763-22608008 protein_coding
  ENST00000613179 CCAR2-201 22615533-22619364 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000308511ENST00000389279ENST00000518989ENST00000520536ENST00000520738ENST00000520861ENST00000521436
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000308511 N/A N/A N/A 0.868±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000389279 N/A 0.639±0.00 5.544±3.02 N/A 1.796±0.00 4.024±0.00 4.672±3.56 2.797±0.00 N/A 6.971±0.00 6.555±3.28 9.623±4.74 21.494±6.26
ENST00000518989 N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.472±0.00 N/A N/A N/A
ENST00000520536 N/A N/A N/A N/A N/A N/A N/A N/A 1.263±0.00 N/A N/A N/A N/A
ENST00000520738 N/A N/A N/A N/A N/A 1.065±0.00 N/A N/A N/A 1.678±0.00 10.393±1.65 N/A N/A
ENST00000520861 8.898±0.00 1.326±0.00 2.250±0.00 4.318±3.19 N/A N/A N/A 2.171±0.00 2.658±1.93 N/A 8.481±1.44 13.879±0.00 16.703±0.00
ENST00000521436 N/A 1.347±0.00 27.072±0.00 18.507±0.00 N/A 8.745±0.00 24.451±0.00 8.185±0.00 14.753±0.00 N/A 18.286±6.93 14.070±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0000993 IDA RNA polymerase II core binding
GO:0004857 IDA enzyme inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005681 IDA spliceosomal complex
GO:0005737 IDA cytoplasm
GO:0005759 IDA mitochondrial matrix
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006397 IEA mRNA processing
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007049 IEA cell cycle
GO:0008380 IEA:IMP RNA splicing
GO:0009411 IMP response to UV
GO:0019899 IPI enzyme binding
GO:0031647 IDA regulation of protein stability
GO:0032435 IDA negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032784 IMP regulation of DNA-templated transcription, elongation
GO:0042752 ISS regulation of circadian rhythm
GO:0043065 IEA:IMP positive regulation of apoptotic process
GO:0043086 IEA negative regulation of catalytic activity
GO:0043653 IDA mitochondrial fragmentation involved in apoptotic process
GO:0044609 IEA:IDA DBIRD complex
GO:0044822 IDA poly(A) RNA binding
GO:1902230 IMP negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:2000003 IMP positive regulation of DNA damage checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038302 CCAR2 cell cycle and apoptosis regulator 2 protein_coding Danio_rerio
ENSMUSG00000033712 Ccar2 cell cycle activator and apoptosis regulator 2 protein_coding Mus_musculus

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