C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: spondin 2, extracellular matrix protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159674 SPON2 9606 - 4:1166932-1208962 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000290902 SPON2-001 1166932-1172873 protein_coding
  ENST00000400762 SPON2-018 1199028-1208962 processed_transcript
  ENST00000431380 SPON2-201 1166937-1173211 protein_coding
  ENST00000502483 SPON2-014 1171889-1195139 protein_coding
  ENST00000502657 SPON2-016 1196827-1208828 processed_transcript
  ENST00000503765 SPON2-002 1171381-1173211 protein_coding
  ENST00000504871 SPON2-011 1172587-1208367 processed_transcript
  ENST00000504909 SPON2-005 1171383-1172298 retained_intron
  ENST00000505653 SPON2-020 1199613-1201357 processed_transcript
  ENST00000506266 SPON2-010 1172575-1208838 processed_transcript
  ENST00000507466 SPON2-007 1171029-1171625 retained_intron
  ENST00000509233 SPON2-012 1172022-1208145 protein_coding
  ENST00000509697 SPON2-008 1169763-1171070 retained_intron
  ENST00000510542 SPON2-019 1204982-1208377 processed_transcript
  ENST00000511672 SPON2-013 1172049-1205088 protein_coding
  ENST00000511679 SPON2-009 1172025-1208846 protein_coding
  ENST00000512150 SPON2-004 1171754-1173127 retained_intron
  ENST00000512888 SPON2-003 1171526-1172845 retained_intron
  ENST00000514490 SPON2-006 1172000-1173170 protein_coding
  ENST00000515004 SPON2-015 1171879-1195134 protein_coding
  ENST00000515553 SPON2-017 1199927-1205094 processed_transcript
  ENST00000617421 SPON2-202 1166937-1208962 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000290902ENST00000400762ENST00000431380ENST00000502657ENST00000506266ENST00000507466ENST00000509697ENST00000617421
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000290902 30.057±0.00 5.990±0.00 N/A 0.965±0.00 23.459±20.74 24.428±0.00 2.626±2.35 18.135±16.70 20.071±17.39 22.730±0.00 2.545±0.00 60.678±2.49 31.866±9.69 9.173±0.00
ENST00000400762 N/A N/A 0.215±0.00 0.300±0.00 0.668±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000431380 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 29.641±0.00 44.982±37.80 2.748±0.00
ENST00000502657 N/A N/A N/A 0.412±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000506266 N/A N/A N/A 0.538±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000507466 N/A N/A N/A N/A N/A 13.365±12.19 N/A N/A N/A N/A N/A N/A N/A 10.774±0.00
ENST00000509697 N/A N/A N/A N/A N/A N/A N/A N/A 1.882±0.00 N/A N/A 5.906±5.00 N/A 1.157±0.00
ENST00000617421 N/A N/A N/A N/A N/A N/A 0.132±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006LO CIL_0006LO_0001 CGP 4:1166932-1249953

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001530 IEA lipopolysaccharide binding
GO:0002448 IEA mast cell mediated immunity
GO:0003823 IEA antigen binding
GO:0005515 IEA protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IEA extracellular space
GO:0007155 IEA cell adhesion
GO:0007411 TAS axon guidance
GO:0008228 IEA opsonization
GO:0031012 IEA extracellular matrix
GO:0032496 IEA response to lipopolysaccharide
GO:0032755 IEA positive regulation of interleukin-6 production
GO:0032760 IEA positive regulation of tumor necrosis factor production
GO:0042742 IEA defense response to bacterium
GO:0043152 IEA induction of bacterial agglutination
GO:0045087 IEA innate immune response
GO:0046872 IEA metal ion binding
GO:0050832 IEA defense response to fungus
GO:0051607 IEA defense response to virus
GO:0060907 IEA positive regulation of macrophage cytokine production
GO:0070062 IDA extracellular vesicular exosome
GO:0071222 IEA cellular response to lipopolysaccharide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002732 spon2b spondin 2b, extracellular matrix protein protein_coding Danio_rerio
ENSMUSG00000037379 Spon2 spondin 2, extracellular matrix protein protein_coding Mus_musculus

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