C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: zinc finger, FYVE domain containing 28
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159733 ZFYVE28 9606 - 4:2269582-2418663 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000290974 ZFYVE28-001 2269598-2418663 protein_coding
  ENST00000503000 ZFYVE28-003 2330162-2418609 protein_coding
  ENST00000504743 ZFYVE28-010 2341316-2364827 processed_transcript
  ENST00000505421 ZFYVE28-011 2342581-2343524 processed_transcript
  ENST00000508184 ZFYVE28-009 2339517-2406665 protein_coding
  ENST00000508471 ZFYVE28-004 2269582-2287715 protein_coding
  ENST00000509171 ZFYVE28-008 2328806-2418651 protein_coding
  ENST00000511071 ZFYVE28-002 2270339-2418636 protein_coding
  ENST00000514248 ZFYVE28-012 2270918-2271751 retained_intron
  ENST00000515169 ZFYVE28-007 2328534-2364804 protein_coding
  ENST00000515312 ZFYVE28-006 2270495-2364877 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000290974ENST00000503000ENST00000505421ENST00000508184ENST00000509171ENST00000511071ENST00000514248ENST00000515169ENST00000515312
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000290974 3.015±0.00 0.880±0.00 N/A 5.398±0.00 0.827±0.06 1.343±0.00 0.859±0.00 4.140±0.00 0.999±0.00 1.441±0.00 0.289±0.00 1.036±0.77 0.709±0.23 3.928±0.00
ENST00000503000 N/A N/A N/A 1.312±0.00 N/A N/A N/A N/A N/A N/A N/A 2.123±0.00 N/A 4.211±0.00
ENST00000505421 0.388±0.00 0.323±0.00 N/A 0.216±0.15 0.534±0.37 0.121±0.05 0.114±0.02 N/A 0.121±0.00 0.170±0.05 N/A 0.157±0.08 0.089±0.05 0.417±0.16
ENST00000508184 N/A N/A N/A N/A N/A N/A N/A N/A 2.007±0.00 N/A 0.847±0.00 N/A N/A N/A
ENST00000509171 N/A N/A N/A N/A N/A N/A 0.406±0.00 N/A N/A N/A 0.099±0.00 N/A N/A N/A
ENST00000511071 N/A N/A N/A N/A N/A 0.630±0.00 0.062±0.00 N/A N/A 0.133±0.00 0.168±0.00 N/A 0.245±0.00 N/A
ENST00000514248 N/A N/A N/A N/A N/A N/A N/A N/A 0.720±0.00 N/A N/A N/A N/A N/A
ENST00000515169 N/A 0.720±0.00 N/A N/A N/A N/A N/A N/A 0.309±0.00 N/A N/A N/A N/A N/A
ENST00000515312 N/A N/A 0.212±0.00 N/A N/A N/A N/A N/A 0.143±0.00 N/A N/A 0.849±0.00 0.352±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000QO CIL_0000QO_0001 CGP 4:2247432-2418663
CIL_0003OB CIL_0003OB_0002 CGP 4:2269582-2462963

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005829 IDA cytosol
GO:0007175 IMP negative regulation of epidermal growth factor-activated receptor activity
GO:0031901 IDA early endosome membrane
GO:0032266 IDA phosphatidylinositol-3-phosphate binding
GO:0042059 IMP negative regulation of epidermal growth factor receptor signaling pathway
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060430 zfyve28 zinc finger, FYVE domain containing 28 protein_coding Danio_rerio
ENSMUSG00000037224 Zfyve28 zinc finger, FYVE domain containing 28 protein_coding Mus_musculus

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