C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adhesion molecule, interacts with CXADR antigen 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160593 AMICA1 9606 - 11:118193740-118225094 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000292067 AMICA1-003 118193963-118213359 protein_coding
  ENST00000356289 AMICA1-001 118193740-118225094 protein_coding
  ENST00000524477 AMICA1-011 118205937-118212885 protein_coding
  ENST00000525565 AMICA1-009 118205951-118224087 protein_coding
  ENST00000526595 AMICA1-007 118194004-118213356 nonsense_mediated_decay
  ENST00000526620 AMICA1-002 118194165-118225021 protein_coding
  ENST00000527877 AMICA1-010 118205949-118225092 nonsense_mediated_decay
  ENST00000529164 AMICA1-006 118197609-118225011 retained_intron
  ENST00000531530 AMICA1-013 118194077-118205390 retained_intron
  ENST00000531536 AMICA1-012 118205659-118212470 retained_intron
  ENST00000533261 AMICA1-004 118193994-118214891 protein_coding
  ENST00000534294 AMICA1-005 118193965-118224994 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000292067ENST00000356289ENST00000525565ENST00000526620ENST00000527877ENST00000529164ENST00000531530ENST00000531536ENST00000533261ENST00000534294
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000292067 N/A N/A N/A N/A N/A 0.244±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000356289 0.239±0.00 N/A 0.232±0.00 N/A N/A 0.770±0.58 0.325±0.00 N/A N/A 7.030±0.00 N/A 0.577±0.22 2.536±1.03 0.484±0.00
ENST00000525565 N/A N/A N/A N/A 2.204±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000526620 0.707±0.00 1.544±0.00 N/A N/A 0.603±0.00 0.488±0.00 0.332±0.11 0.387±0.00 0.575±0.34 N/A N/A 2.240±1.36 3.425±0.40 0.593±0.00
ENST00000527877 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.305±0.00 N/A N/A N/A
ENST00000529164 N/A N/A N/A 0.098±0.07 0.699±0.00 N/A 0.438±0.00 2.017±0.00 1.138±0.00 4.773±0.00 0.099±0.00 N/A N/A N/A
ENST00000531530 N/A N/A N/A N/A 0.684±0.00 N/A N/A N/A 0.419±0.00 2.863±0.00 N/A 0.758±0.00 N/A 0.225±0.00
ENST00000531536 N/A N/A N/A 0.435±0.00 N/A N/A N/A N/A N/A 13.824±0.00 N/A 4.853±0.00 N/A 1.156±0.00
ENST00000533261 0.641±0.00 2.640±0.00 N/A N/A 1.999±0.00 N/A 0.181±0.00 0.560±0.21 0.915±0.00 9.937±0.00 N/A 1.343±0.64 2.577±1.09 0.842±0.32
ENST00000534294 N/A 0.846±0.00 N/A 0.016±0.00 0.168±0.04 0.854±0.00 0.078±0.00 N/A 0.235±0.00 1.324±0.61 N/A 0.106±0.00 N/A 0.094±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081E CIL_00081E_0001 VISTA 11:118137591-118740525

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005178 IPI integrin binding
GO:0005515 IEA protein binding
GO:0005886 IDA plasma membrane
GO:0005923 IDA tight junction
GO:0007157 IDA heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007596 TAS blood coagulation
GO:0016021 IEA integral component of membrane
GO:0030593 IMP neutrophil chemotaxis
GO:0035696 IMP monocyte extravasation
GO:0042803 IDA protein homodimerization activity
GO:0046629 ISS gamma-delta T cell activation
GO:0050776 TAS regulation of immune response
GO:0050839 IPI cell adhesion molecule binding
GO:0050900 TAS leukocyte migration
GO:0060054 ISS positive regulation of epithelial cell proliferation involved in wound healing
GO:0072672 IMP neutrophil extravasation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000048534 Amica1 adhesion molecule, interacts with CXADR antigen 1 protein_coding Mus_musculus

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