C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NLR family member X1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160703 NLRX1 9606 + 11:119166568-119184016 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000292199 NLRX1-001 119168729-119184014 protein_coding
  ENST00000409109 NLRX1-004 119168764-119184016 protein_coding
  ENST00000409265 NLRX1-201 119168334-119184014 protein_coding
  ENST00000409991 NLRX1-003 119168728-119184012 protein_coding
  ENST00000422249 NLRX1-009 119168408-119173630 protein_coding
  ENST00000449394 NLRX1-008 119168337-119173662 protein_coding
  ENST00000454811 NLRX1-006 119168188-119173703 protein_coding
  ENST00000468765 NLRX1-010 119169147-119173692 processed_transcript
  ENST00000469103 NLRX1-013 119177777-119180198 processed_transcript
  ENST00000474751 NLRX1-011 119168713-119173662 processed_transcript
  ENST00000481860 NLRX1-012 119168742-119181357 retained_intron
  ENST00000482180 NLRX1-007 119166568-119173705 processed_transcript
  ENST00000524562 NLRX1-014 119173016-119175040 retained_intron
  ENST00000525863 NLRX1-005 119171356-119184016 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000292199ENST00000409109ENST00000409265ENST00000409991ENST00000422249ENST00000474751ENST00000524562ENST00000525863
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000292199 1.104±0.00 N/A N/A N/A N/A 0.985±0.00 1.197±0.40 N/A N/A 1.578±0.00 3.575±0.00 2.006±1.32 4.706±0.00 3.033±0.00
ENST00000409109 1.187±0.00 1.018±0.00 N/A 0.699±0.00 1.327±1.17 N/A 0.960±0.48 0.907±0.00 0.744±0.13 N/A 0.916±0.00 1.448±0.74 0.888±0.00 0.604±0.09
ENST00000409265 N/A N/A N/A 0.147±0.00 0.201±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000409991 N/A 3.177±0.00 N/A N/A N/A 0.231±0.00 1.085±0.00 N/A N/A N/A N/A 3.533±0.16 6.145±0.26 0.632±0.00
ENST00000422249 N/A N/A 0.775±0.00 N/A N/A N/A N/A N/A N/A N/A 2.463±0.00 N/A N/A N/A
ENST00000474751 N/A N/A 0.313±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000524562 N/A N/A N/A N/A N/A N/A N/A 0.523±0.00 N/A N/A N/A N/A N/A N/A
ENST00000525863 N/A N/A N/A 0.624±0.00 0.121±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 1.504±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005739 IEA mitochondrion
GO:0005741 TAS mitochondrial outer membrane
GO:0016032 IEA viral process
GO:0032480 TAS negative regulation of type I interferon production
GO:0032688 IEA negative regulation of interferon-beta production
GO:0032715 IEA negative regulation of interleukin-6 production
GO:0039536 IEA negative regulation of RIG-I signaling pathway
GO:0043124 IEA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 TAS innate immune response
GO:0045824 IEA negative regulation of innate immune response
GO:0050728 IEA negative regulation of inflammatory response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073724 nlrx1 NLR family member X1 protein_coding Danio_rerio
ENSMUSG00000032109 Nlrx1 NLR family member X1 protein_coding Mus_musculus

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