C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NLR family member X1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032109 Nlrx1 10090 - 9:44252713-44268599 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034621 Nlrx1-201 44252713-44268491 protein_coding
  ENSMUST00000168499 Nlrx1-202 44252713-44268599 protein_coding
  ENSMUST00000169651 Nlrx1-203 44252713-44268187 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034621ENSMUST00000168499ENSMUST00000169651
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034621 N/A N/A N/A 0.424±0.00 N/A N/A N/A N/A 0.233±0.00 N/A N/A N/A 0.923±0.43 0.358±0.00
ENSMUST00000168499 3.376±1.10 7.223±0.70 1.943±0.03 0.854±0.08 4.294±1.85 10.271±1.35 2.428±1.29 1.800±0.84 1.598±1.10 3.397±1.03 1.861±0.00 3.435±1.65 2.323±0.97 0.389±0.10
ENSMUST00000169651 1.598±0.24 2.946±1.02 N/A 1.553±0.00 2.062±0.83 3.000±0.00 2.054±0.61 1.400±0.55 0.930±0.52 1.740±0.00 3.213±1.06 2.543±0.97 2.516±0.00 0.238±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00068P CIL_00068P_0002 CGP 9:44247312-44268599
CIL_0006Q2 CIL_0006Q2_0002 CGP 9:44252713-44288615

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005741 IEA mitochondrial outer membrane
GO:0016032 IEA viral process
GO:0032688 IMP negative regulation of interferon-beta production
GO:0032715 IMP negative regulation of interleukin-6 production
GO:0039536 IMP negative regulation of RIG-I signaling pathway
GO:0043124 IMP negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 IEA innate immune response
GO:0045824 IMP negative regulation of innate immune response
GO:0050728 IMP negative regulation of inflammatory response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073724 nlrx1 NLR family member X1 protein_coding Danio_rerio
ENSG00000160703 NLRX1 NLR family member X1 protein_coding Homo_sapiens

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