C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin, light chain 3, alkali; ventricular, skeletal, slow
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160808 MYL3 9606 - 3:46857872-46882169 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000292327 MYL3-001 46857872-46863483 protein_coding
  ENST00000395869 MYL3-002 46857872-46863442 protein_coding
  ENST00000431168 MYL3-003 46860979-46882169 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000292327ENST00000395869ENST00000431168
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000292327 N/A N/A 0.808±0.00 0.056±0.00 25.300±0.00 0.066±0.00 348.120±0.00 4.721±4.56 1.238±0.51 0.277±0.02 249.767±230.02 1.090±0.51 8.592±7.90 1.269±0.00
ENST00000395869 0.745±0.00 0.207±0.00 N/A 1.026±0.97 6.091±0.00 N/A 412.088±346.83 1.852±0.00 N/A N/A 58.594±47.41 0.332±0.21 4.168±3.59 1.624±0.00
ENST00000431168 N/A N/A N/A N/A N/A 0.122±0.07 N/A N/A 1.164±0.00 N/A N/A 0.593±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002026 IMP regulation of the force of heart contraction
GO:0003774 IEA motor activity
GO:0003785 IDA actin monomer binding
GO:0005509 IEA calcium ion binding
GO:0005829 TAS cytosol
GO:0005859 TAS muscle myosin complex
GO:0006942 IMP regulation of striated muscle contraction
GO:0007519 IEA skeletal muscle tissue development
GO:0008152 IEA metabolic process
GO:0008307 TAS structural constituent of muscle
GO:0016459 IEA myosin complex
GO:0030017 TAS sarcomere
GO:0030049 TAS muscle filament sliding
GO:0031672 IDA A band
GO:0031674 IDA I band
GO:0032038 NAS myosin II heavy chain binding
GO:0032781 ISS positive regulation of ATPase activity
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060048 IMP cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042245 zgc:66286 myosin, light chain 3, alkali; ventricular, skeletal, slow protein_coding Danio_rerio
ENSMUSG00000059741 Myl3 myosin, light polypeptide 3 protein_coding Mus_musculus

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