C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 11, subfamily B, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160882 CYP11B1 9606 - 8:142872356-142879846 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000292427 CYP11B1-001 142873254-142879846 protein_coding
  ENST00000314111 CYP11B1-004 142872356-142879846 retained_intron
  ENST00000377675 CYP11B1-003 142873825-142879820 protein_coding
  ENST00000517471 CYP11B1-002 142873824-142879824 protein_coding
  ENST00000519285 CYP11B1-005 142872357-142875797 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeLungOvaryTestisENST00000292427ENST00000517471ENST00000519285
Transcript ID Adipose Lung Ovary Testis
ENST00000292427 N/A N/A N/A 0.246±0.00
ENST00000517471 N/A N/A 0.028±0.00 0.297±0.09
ENST00000519285 0.006±0.00 0.088±0.00 0.280±0.00 0.057±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00031J CIL_00031J_0001 CGP 8:142834247-142916506
CIL_0002NU CIL_0002NU_0001 CGP 8:142872356-142917843

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IEA monooxygenase activity
GO:0004507 IMP steroid 11-beta-monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005739 IDA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006700 IDA C21-steroid hormone biosynthetic process
GO:0006704 TAS glucocorticoid biosynthetic process
GO:0006705 TAS mineralocorticoid biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0006955 TAS immune response
GO:0008202 TAS steroid metabolic process
GO:0008217 IMP regulation of blood pressure
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IC:IEA heme binding
GO:0032342 IMP aldosterone biosynthetic process
GO:0032870 IEP cellular response to hormone stimulus
GO:0034651 IMP cortisol biosynthetic process
GO:0035865 IEP cellular response to potassium ion
GO:0042593 TAS glucose homeostasis
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042014 cyp11c1 cytochrome P450, family 11, subfamily C, polypeptide 1 protein_coding Danio_rerio
ENSMUSG00000022589 Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 protein_coding Mus_musculus
ENSMUSG00000075604 Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 protein_coding Mus_musculus

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