C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cytochrome P450, family 11, subfamily B, polypeptide 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000517471 CYP11B1-002 ENSG00000160882 9606 - 8:142873824-142879824 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; OvaryTestisENST00000517471
Transcript ID Ovary Testis
ENST00000517471 0.028±0.00 0.297±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00031J CIL_00031J_0001 CGP 8:142834247-142916506
CIL_0002NU CIL_0002NU_0001 CGP 8:142872356-142917843

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004507 IMP steroid 11-beta-monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005739 IDA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006700 IDA C21-steroid hormone biosynthetic process
GO:0006704 TAS glucocorticoid biosynthetic process
GO:0006705 TAS mineralocorticoid biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0006955 TAS immune response
GO:0008202 TAS steroid metabolic process
GO:0008217 IMP regulation of blood pressure
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IC:IEA heme binding
GO:0032342 IMP aldosterone biosynthetic process
GO:0032870 IEP cellular response to hormone stimulus
GO:0034651 IMP cortisol biosynthetic process
GO:0035865 IEP cellular response to potassium ion
GO:0042593 TAS glucose homeostasis
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000167634 Cyp11b2-001 protein_coding Mus_musculus 0 603
ENSMUST00000170259 Cyp11b1-001 protein_coding Mus_musculus 0 436

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