C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dishevelled segment polarity protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000161202 DVL3 9606 + 3:184155388-184173610 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000313143 DVL3-001 184155388-184173610 protein_coding
  ENST00000423300 DVL3-005 184156775-184166509 protein_coding
  ENST00000431765 DVL3-002 184155560-184170873 protein_coding
  ENST00000435708 DVL3-006 184155558-184164517 nonsense_mediated_decay
  ENST00000462665 DVL3-007 184155562-184164912 processed_transcript
  ENST00000467873 DVL3-009 184164647-184165478 retained_intron
  ENST00000478247 DVL3-004 184163677-184170876 retained_intron
  ENST00000478639 DVL3-008 184166194-184166701 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000313143ENST00000423300ENST00000431765ENST00000478247
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000313143 9.116±0.00 10.765±0.00 N/A 7.648±0.00 5.184±3.98 5.994±5.57 7.536±6.76 4.573±4.17 2.739±1.29 13.490±0.00 17.150±0.00 22.694±11.76 27.659±4.06 9.850±5.57
ENST00000423300 N/A N/A N/A N/A 4.953±0.00 N/A N/A 1.820±0.00 3.841±0.00 0.977±0.00 N/A 4.194±0.00 N/A N/A
ENST00000431765 6.808±0.00 N/A 1.200±0.00 3.499±0.00 5.707±0.00 2.185±0.00 1.499±0.00 N/A 2.252±0.00 N/A 1.857±0.00 16.213±11.87 14.330±0.00 16.410±0.00
ENST00000478247 6.699±0.00 7.052±0.00 1.965±0.00 7.413±4.57 3.395±1.56 5.379±4.60 N/A 6.500±0.00 2.149±0.00 0.974±0.00 N/A 10.548±7.37 N/A 12.106±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005G3 CIL_0005G3_0001 CGP 3:184135038-184684758
CIL_0003YF CIL_0003YF_0002 CGP 3:184155388-184184091

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0002020 IPI protease binding
GO:0003007 IEA heart morphogenesis
GO:0003148 IBA outflow tract septum morphogenesis
GO:0005102 IPI receptor binding
GO:0005109 IPI frizzled binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005938 IBA cell cortex
GO:0008013 IDA beta-catenin binding
GO:0016055 IDA Wnt signaling pathway
GO:0035556 IEA intracellular signal transduction
GO:0035567 IMP non-canonical Wnt signaling pathway
GO:0038031 ISS non-canonical Wnt signaling pathway via JNK cascade
GO:0042493 IEA response to drug
GO:0043507 IMP positive regulation of JUN kinase activity
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046982 IDA protein heterodimerization activity
GO:0060026 IBA convergent extension
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060071 IDA Wnt signaling pathway, planar cell polarity pathway
GO:0090103 IBA cochlea morphogenesis
GO:0090179 IBA planar cell polarity pathway involved in neural tube closure

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002148 DVL3 (1 of 2) dishevelled segment polarity protein 3 protein_coding Danio_rerio
ENSDARG00000015707 dvl3a dishevelled, dsh homolog 3a (Drosophila) protein_coding Danio_rerio
ENSMUSG00000003233 Dvl3 dishevelled 3, dsh homolog (Drosophila) protein_coding Mus_musculus

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