C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dishevelled 3, dsh homolog (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003233 Dvl3 10090 + 16:20516982-20532520 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003318 Dvl3-001 20516982-20531650 protein_coding
  ENSMUST00000169552 Dvl3-002 20517186-20525319 retained_intron
  ENSMUST00000171572 Dvl3-003 20517064-20532520 protein_coding
  ENSMUST00000171774 Dvl3-004 20517106-20531646 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003318ENSMUST00000171572ENSMUST00000171774
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003318 N/A 7.306±0.00 N/A 17.969±5.72 3.341±0.47 6.619±2.36 N/A N/A 1.756±0.15 5.837±0.00 N/A 6.256±4.01 5.565±0.82 1.853±0.00
ENSMUST00000171572 3.760±1.88 4.782±0.60 10.253±0.00 8.475±1.19 3.078±0.00 3.987±0.33 5.672±1.94 3.370±1.34 2.709±1.22 3.557±0.41 4.985±1.78 6.469±1.15 4.913±0.14 0.985±0.17
ENSMUST00000171774 N/A N/A N/A 15.503±0.00 N/A N/A N/A N/A N/A N/A N/A 22.472±0.00 30.274±3.11 0.900±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005G3 CIL_0005G3_0002 CGP 16:20498817-20532520
CIL_0003YF CIL_0003YF_0003 CGP 16:20516982-20544909

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0002020 IEA protease binding
GO:0003007 IGI heart morphogenesis
GO:0003148 IMP outflow tract septum morphogenesis
GO:0005102 IEA receptor binding
GO:0005109 IBA frizzled binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005938 IBA cell cortex
GO:0008013 IBA beta-catenin binding
GO:0016055 IEA Wnt signaling pathway
GO:0023051 IBA regulation of signaling
GO:0035556 IEA intracellular signal transduction
GO:0035567 IEA non-canonical Wnt signaling pathway
GO:0038031 IDA non-canonical Wnt signaling pathway via JNK cascade
GO:0042493 IEA response to drug
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0045893 IBA positive regulation of transcription, DNA-templated
GO:0046982 IEA protein heterodimerization activity
GO:0060026 IBA convergent extension
GO:0060070 IBA canonical Wnt signaling pathway
GO:0060071 TAS Wnt signaling pathway, planar cell polarity pathway
GO:0090103 IGI cochlea morphogenesis
GO:0090179 IGI planar cell polarity pathway involved in neural tube closure

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002148 DVL3 (1 of 2) dishevelled segment polarity protein 3 protein_coding Danio_rerio
ENSDARG00000015707 dvl3a dishevelled, dsh homolog 3a (Drosophila) protein_coding Danio_rerio
ENSG00000161202 DVL3 dishevelled segment polarity protein 3 protein_coding Homo_sapiens

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