C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adaptor-related protein complex 2, mu 1 subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000161203 AP2M1 9606 + 3:184174689-184184091 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000292807 AP2M1-003 184174855-184184091 protein_coding
  ENST00000382456 AP2M1-001 184174689-184184091 protein_coding
  ENST00000411763 AP2M1-002 184174855-184183662 protein_coding
  ENST00000427072 AP2M1-009 184174855-184179122 protein_coding
  ENST00000431779 AP2M1-017 184176979-184180915 protein_coding
  ENST00000432591 AP2M1-015 184176949-184182054 protein_coding
  ENST00000439647 AP2M1-005 184176778-184184048 protein_coding
  ENST00000442686 AP2M1-022 184182015-184183298 protein_coding
  ENST00000448139 AP2M1-011 184174882-184180893 protein_coding
  ENST00000455925 AP2M1-014 184174949-184179122 protein_coding
  ENST00000460862 AP2M1-013 184174905-184180212 processed_transcript
  ENST00000461733 AP2M1-007 184180509-184184065 processed_transcript
  ENST00000463935 AP2M1-020 184181403-184182181 retained_intron
  ENST00000466598 AP2M1-012 184174886-184179349 retained_intron
  ENST00000468048 AP2M1-006 184180216-184181685 retained_intron
  ENST00000472560 AP2M1-016 184176951-184181286 retained_intron
  ENST00000476434 AP2M1-019 184181195-184182080 retained_intron
  ENST00000480260 AP2M1-021 184181619-184182303 retained_intron
  ENST00000484469 AP2M1-008 184174846-184177869 retained_intron
  ENST00000487958 AP2M1-010 184174855-184180476 retained_intron
  ENST00000490151 AP2M1-018 184180064-184181793 retained_intron
  ENST00000621863 AP2M1-201 184176994-184183616 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000292807ENST00000382456ENST00000411763ENST00000439647ENST00000621863
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000292807 170.877±0.00 155.445±0.00 5.131±0.00 166.324±103.58 72.297±64.63 85.094±79.81 56.947±46.44 168.531±0.00 33.195±19.49 133.265±0.00 37.410±25.28 96.583±54.24 189.084±28.26 137.732±42.69
ENST00000382456 N/A N/A 2.342±0.00 N/A 4.624±0.00 N/A N/A 7.399±0.00 7.247±3.44 N/A N/A 33.298±3.47 33.535±9.05 N/A
ENST00000411763 N/A N/A 4.147±0.00 26.416±0.00 8.734±0.00 10.950±0.00 N/A 13.887±0.00 N/A 10.082±0.00 N/A 11.271±0.00 N/A N/A
ENST00000439647 N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.118±0.00 N/A N/A N/A N/A
ENST00000621863 N/A N/A 2.696±0.00 N/A N/A 4.876±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005G3 CIL_0005G3_0001 CGP 3:184135038-184684758
CIL_0003YF CIL_0003YF_0002 CGP 3:184155388-184184091
CIL_0005G2 CIL_0005G2_0001 CGP 3:184174689-184194012

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005215 TAS transporter activity
GO:0005515 IPI:IEA protein binding
GO:0005739 IEA mitochondrion
GO:0005765 TAS lysosomal membrane
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005905 IEA coated pit
GO:0006810 IEA transport
GO:0006886 IEA intracellular protein transport
GO:0006897 IEA endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008289 IEA lipid binding
GO:0016032 TAS viral process
GO:0016192 IEA vesicle-mediated transport
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030131 IEA clathrin adaptor complex
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050690 TAS regulation of defense response to virus by virus
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:1903077 IMP negative regulation of protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002790 ap2m1a adaptor-related protein complex 2, mu 1 subunit, a protein_coding Danio_rerio
ENSDARG00000033899 ap2m1b adaptor-related protein complex 2, mu 1 subunit, b protein_coding Danio_rerio
ENSMUSG00000022841 Ap2m1 adaptor-related protein complex 2, mu 1 subunit protein_coding Mus_musculus

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