C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 3-hydroxyanthranilate 3,4-dioxygenase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162882 HAAO 9606 - 2:42767089-42792593 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000294973 HAAO-001 42767089-42792592 protein_coding
  ENST00000402268 HAAO-005 42782787-42792567 retained_intron
  ENST00000402698 HAAO-002 42767120-42792574 retained_intron
  ENST00000404451 HAAO-006 42767667-42792531 retained_intron
  ENST00000406007 HAAO-007 42767089-42769893 retained_intron
  ENST00000406924 HAAO-008 42769887-42792593 retained_intron
  ENST00000431905 HAAO-004 42769711-42792572 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000294973ENST00000402268ENST00000402698ENST00000404451ENST00000406007ENST00000406924ENST00000431905
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000294973 1.494±0.00 3.794±0.00 1.366±0.00 0.599±0.00 5.270±0.00 0.939±0.13 1.340±0.00 16.716±8.00 52.171±0.00 6.222±0.00 0.743±0.00 6.705±4.64 9.112±4.19 2.328±1.36
ENST00000402268 N/A N/A 3.028±0.00 0.179±0.03 0.170±0.00 N/A N/A 4.125±0.00 1.061±0.00 N/A N/A 0.310±0.00 N/A 0.180±0.00
ENST00000402698 N/A 0.697±0.00 N/A 0.138±0.00 N/A 1.286±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000404451 N/A N/A N/A N/A N/A 0.403±0.00 N/A N/A N/A N/A N/A 1.734±0.00 N/A N/A
ENST00000406007 0.505±0.00 N/A N/A 0.415±0.00 N/A N/A N/A N/A 1.096±0.00 0.766±0.00 0.569±0.00 N/A 3.557±0.00 0.634±0.00
ENST00000406924 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.375±0.00 N/A 0.278±0.00
ENST00000431905 N/A N/A N/A 0.163±0.00 N/A N/A N/A N/A N/A N/A 0.080±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XL CIL_0001XL_0001 CGP 2:42767089-43226609

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000334 IDA:IEA 3-hydroxyanthranilate 3,4-dioxygenase activity
GO:0005506 IEA iron ion binding
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006569 TAS tryptophan catabolic process
GO:0008198 IDA ferrous iron binding
GO:0009055 NAS electron carrier activity
GO:0010043 IDA response to zinc ion
GO:0019805 NAS quinolinate biosynthetic process
GO:0019825 IEA oxygen binding
GO:0031966 IEA mitochondrial membrane
GO:0034354 IEA 'de novo' NAD biosynthetic process from tryptophan
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0043420 IEA anthranilate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046686 IDA response to cadmium ion
GO:0046872 IEA metal ion binding
GO:0046874 IEA quinolinate metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070050 IMP neuron cellular homeostasis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076487 haao 3-hydroxyanthranilate 3,4-dioxygenase protein_coding Danio_rerio
ENSMUSG00000000673 Haao 3-hydroxyanthranilate 3,4-dioxygenase protein_coding Mus_musculus

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